Homo sapiens

Gene ID: ENSG00000116852
Biological name :KIF21B
Synonyms : KIF21B / kinesin family member 21B / O75037
Possible biological names infered from orthology :
Species: Homo sapiens
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 200969390
Gene end: 201023700
Corresponding Affymetrix probe sets: 204411_at (Human Genome U133 Plus 2.0 Array)   
Cross references: Ensembl peptide - ENSP00000328494
Ensembl peptide - ENSP00000353724
Ensembl peptide - ENSP00000411831
Ensembl peptide - ENSP00000433808
NCBI entrez gene - 23046     See in Manteia.
OMIM - 608322
RefSeq - XM_017000732
RefSeq - NM_001252100
RefSeq - NM_001252102
RefSeq - NM_001252103
RefSeq - NM_017596
RefSeq - XM_017000731
RefSeq Peptide - NP_001239032
RefSeq Peptide - NP_060066
RefSeq Peptide - NP_001239029
RefSeq Peptide - NP_001239031
swissprot - O75037
Ensembl - ENSG00000116852
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif21bENSDARG00000009733Danio rerio
 KIF21BENSGALG00000034347Gallus gallus
 Kif21bENSMUSG00000041642Mus musculus

Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KIF21A / Q7Z4S6 / kinesin family member 21AENSG0000013911660
KIF4A / O95239 / kinesin family member 4AENSG0000009088922
KIF4B / Q2VIQ3 / kinesin family member 4BENSG0000022665021
KIF27 / Q86VH2 / kinesin family member 27ENSG0000016511521
CENPE / Q02224 / centromere protein EENSG0000013877819
KIF7 / Q2M1P5 / kinesin family member 7ENSG0000016681319
KIF5A / Q12840 / kinesin family member 5AENSG0000015598016
KIF17 / Q9P2E2 / kinesin family member 17ENSG0000011724516
KIF15 / Q9NS87 / kinesin family member 15ENSG0000016380816
KIF11 / P52732 / kinesin family member 11ENSG0000013816014
KIF5B / P33176 / kinesin family member 5BENSG0000017075914
KIF5C / O60282 / kinesin family member 5CENSG0000016828014
KIF3C / O14782 / kinesin family member 3CENSG0000008473113
KIF3B / O15066 / kinesin family member 3BENSG0000010135013
KIF3A / Q9Y496 / kinesin family member 3AENSG0000013143712

Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR001752  Kinesin motor domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR036322  WD40-repeat-containing domain superfamily
 IPR036961  Kinesin motor domain superfamily

Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003777 microtubule motor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016887 ATPase activity IBA

Pathways (from Reactome)
Pathway description
COPI-dependent Golgi-to-ER retrograde traffic

Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match

Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match


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