Homo sapiens

Gene ID: ENSG00000084731
Biological name :KIF3C
Synonyms : KIF3C / kinesin family member 3C / O14782
Possible biological names infered from orthology :
Species: Homo sapiens
Chr. number: 2
Strand: -1
Band: p23.3
Gene start: 25926596
Gene end: 25982749
Corresponding Affymetrix probe sets: 203389_at (Human Genome U133 Plus 2.0 Array)   203390_s_at (Human Genome U133 Plus 2.0 Array)   
Cross references: Ensembl peptide - ENSP00000385030
Ensembl peptide - ENSP00000410407
Ensembl peptide - ENSP00000393676
Ensembl peptide - ENSP00000264712
NCBI entrez gene - 3797     See in Manteia.
OMIM - 602845
RefSeq - XM_005264299
RefSeq - NM_002254
RefSeq Peptide - NP_002245
swissprot - F8WER6
swissprot - A2RU78
swissprot - O14782
swissprot - F8WAR6
Ensembl - ENSG00000084731
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif3caENSDARG00000017162Danio rerio
 kif3cbENSDARG00000079500Danio rerio
 KIF3CENSGALG00000026973Gallus gallus
 Kif3cENSMUSG00000020668Mus musculus

Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KIF3B / O15066 / kinesin family member 3BENSG0000010135062
KIF3A / Q9Y496 / kinesin family member 3AENSG0000013143741
KIF17 / Q9P2E2 / kinesin family member 17ENSG0000011724538
KIF11 / P52732 / kinesin family member 11ENSG0000013816029
KIF7 / Q2M1P5 / kinesin family member 7ENSG0000016681327
KIF21B / O75037 / kinesin family member 21BENSG0000011685226
KIF5B / P33176 / kinesin family member 5BENSG0000017075926
CENPE / Q02224 / centromere protein EENSG0000013877826
KIF27 / Q86VH2 / kinesin family member 27ENSG0000016511526
KIF4A / O95239 / kinesin family member 4AENSG0000009088926
KIF5A / Q12840 / kinesin family member 5AENSG0000015598026
KIF5C / O60282 / kinesin family member 5CENSG0000016828025
KIF4B / Q2VIQ3 / kinesin family member 4BENSG0000022665025
KIF15 / Q9NS87 / kinesin family member 15ENSG0000016380825
KIF21A / Q7Z4S6 / kinesin family member 21AENSG0000013911625

Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR036961  Kinesin motor domain superfamily

Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS
 biological_processGO:0007018 microtubule-based movement TAS
 biological_processGO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II TAS
 biological_processGO:0035735 intraciliary transport involved in cilium assembly TAS
 biological_processGO:0072384 organelle transport along microtubule IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex TAS
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium TAS
 cellular_componentGO:0097542 ciliary tip TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity TAS
 molecular_functionGO:0003777 microtubule motor activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016887 ATPase activity IBA

Pathways (from Reactome)
Pathway description
MHC class II antigen presentation
Intraflagellar transport
COPI-dependent Golgi-to-ER retrograde traffic

Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match

Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131437 KIF3A / Q9Y496 / kinesin family member 3A  / complex / reaction
 ENSG00000109083 IFT20 / Q8IY31 / intraflagellar transport 20  / complex / reaction
 ENSG00000075945 KIFAP3 / Q92845 / kinesin associated protein 3  / complex / reaction


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