ENSG00000080910


Homo sapiens

Features
Gene ID: ENSG00000080910
  
Biological name :CFHR2
  
Synonyms : CFHR2 / complement factor H related 2 / P36980
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q31.3
Gene start: 196943772
Gene end: 196959226
  
Corresponding Affymetrix probe sets: 206910_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356385
Ensembl peptide - ENSP00000476677
NCBI entrez gene - 3080     See in Manteia.
OMIM - 600889
RefSeq - XM_017001109
RefSeq - NM_005666
RefSeq - XM_011509458
RefSeq - XM_011509459
RefSeq - XM_011509460
RefSeq - XM_005245113
RefSeq Peptide - NP_005657
swissprot - P36980
swissprot - V9GYE7
Ensembl - ENSG00000080910
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000002431Gallus gallus
 Cfhr1ENSMUSG00000057037Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BX248415.1ENSG00000276911100
CFHR1 / Q03591 / complement factor H related 1ENSG0000024441486
CFHR5 / Q9BXR6 / complement factor H related 5ENSG0000013438973
CFH / P08603 / complement factor HENSG0000000097153
CFHR4 / Q92496 / complement factor H related 4ENSG0000013436537
CFHR3 / Q02985 / complement factor H related 3ENSG0000011678536
F13B / P05160 / coagulation factor XIII B chainENSG0000014327830
C4BPA / P04003 / complement component 4 binding protein alphaENSG0000012383820
SELP / P16109 / selectin PENSG0000017417516
SELE / P16581 / selectin EENSG0000000790815
CD46 / P15529 / CD46 moleculeENSG0000011733515
CD55 / P08174 / CD55 molecule (Cromer blood group)ENSG0000019635214
APOH / P02749 / apolipoprotein HENSG0000009158314
SELL / P14151 / selectin LENSG0000018840410


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR035976  Sushi/SCR/CCP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030449 regulation of complement activation TAS
 biological_processGO:0032091 negative regulation of protein binding IMP
 biological_processGO:0045919 positive regulation of cytolysis IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000125730 C3 / P01024 / complement C3  / complex / reaction
 ENSG00000080910 CFHR2 / P36980 / complement factor H related 2  / complex






 

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