ENSG00000091583


Homo sapiens

Features
Gene ID: ENSG00000091583
  
Biological name :APOH
  
Synonyms : APOH / apolipoprotein H / P02749
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q24.2
Gene start: 66212033
Gene end: 66256525
  
Corresponding Affymetrix probe sets: 205216_s_at (Human Genome U133 Plus 2.0 Array)   231359_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000205948
Ensembl peptide - ENSP00000463553
Ensembl peptide - ENSP00000464301
Ensembl peptide - ENSP00000462260
NCBI entrez gene - 350     See in Manteia.
OMIM - 138700
RefSeq - NM_000042
RefSeq Peptide - NP_000033
swissprot - P02749
swissprot - J3KS17
swissprot - J3QLI0
swissprot - J3QRN2
Ensembl - ENSG00000091583
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 APOHENSGALG00000033376Gallus gallus
 ApohENSMUSG00000000049Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
C4BPA / P04003 / complement component 4 binding protein alphaENSG0000012383827
CFH / P08603 / complement factor HENSG0000000097121
CD46 / P15529 / CD46 moleculeENSG0000011733521
SELP / P16109 / selectin PENSG0000017417520
CD55 / P08174 / CD55 molecule (Cromer blood group)ENSG0000019635219
F13B / P05160 / coagulation factor XIII B chainENSG0000014327819
CFHR5 / Q9BXR6 / complement factor H related 5ENSG0000013438919
SELE / P16581 / selectin EENSG0000000790818
SELL / P14151 / selectin LENSG0000018840413
CFHR1 / Q03591 / complement factor H related 1ENSG0000024441412
CFHR2 / P36980 / complement factor H related 2ENSG0000008091011
BX248415.1ENSG0000027691111
CFHR4 / Q92496 / complement factor H related 4ENSG000001343658
CFHR3 / Q02985 / complement factor H related 3ENSG000001167854


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR015104  Beta-2-glycoprotein-1 fifth domain
 IPR035976  Sushi/SCR/CCP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001937 negative regulation of endothelial cell proliferation IDA
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0006641 triglyceride metabolic process IDA
 biological_processGO:0007597 blood coagulation, intrinsic pathway IDA
 biological_processGO:0010596 negative regulation of endothelial cell migration IDA
 biological_processGO:0016525 negative regulation of angiogenesis IDA
 biological_processGO:0030193 regulation of blood coagulation IEA
 biological_processGO:0030194 positive regulation of blood coagulation TAS
 biological_processGO:0030195 negative regulation of blood coagulation IDA
 biological_processGO:0031639 plasminogen activation IDA
 biological_processGO:0033033 negative regulation of myeloid cell apoptotic process IDA
 biological_processGO:0034197 triglyceride transport ISS
 biological_processGO:0034392 negative regulation of smooth muscle cell apoptotic process IDA
 biological_processGO:0051006 positive regulation of lipoprotein lipase activity IDA
 biological_processGO:0051917 regulation of fibrinolysis IDA
 biological_processGO:0051918 negative regulation of fibrinolysis IDA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0031089 platelet dense granule lumen TAS
 cellular_componentGO:0034361 very-low-density lipoprotein particle IDA
 cellular_componentGO:0034364 high-density lipoprotein particle IDA
 cellular_componentGO:0042627 chylomicron IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding IDA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0008289 lipid binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0060230 lipoprotein lipase activator activity IDA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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