ENSG00000101445


Homo sapiens

Features
Gene ID: ENSG00000101445
  
Biological name :PPP1R16B
  
Synonyms : PPP1R16B / protein phosphatase 1 regulatory subunit 16B / Q96T49
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.23
Gene start: 38805705
Gene end: 38923024
  
Corresponding Affymetrix probe sets: 212750_at (Human Genome U133 Plus 2.0 Array)   233813_at (Human Genome U133 Plus 2.0 Array)   41577_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000299824
Ensembl peptide - ENSP00000362428
NCBI entrez gene - 26051     See in Manteia.
OMIM - 613275
RefSeq - XM_017027785
RefSeq - NM_001172735
RefSeq - NM_015568
RefSeq - XM_011528768
RefSeq - XM_011528769
RefSeq Peptide - NP_001166206
RefSeq Peptide - NP_056383
swissprot - Q96T49
Ensembl - ENSG00000101445
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp1r16bENSDARG00000079860Danio rerio
 PPP1R16BENSGALG00000003568Gallus gallus
 Q8VHQ3ENSMUSG00000037754Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96I34 / PPP1R16A / protein phosphatase 1 regulatory subunit 16AENSG0000016097247
O60237 / PPP1R12B / protein phosphatase 1 regulatory subunit 12BENSG0000007715728
O14974 / PPP1R12A / protein phosphatase 1 regulatory subunit 12AENSG0000005827227
Q9BZL4 / PPP1R12C / protein phosphatase 1 regulatory subunit 12CENSG0000012550326
Q13625 / TP53BP2 / tumor protein p53 binding protein 2ENSG0000014351414
Q96KQ4 / PPP1R13B / protein phosphatase 1 regulatory subunit 13BENSG0000008880814
Q86WC6 / PPP1R27 / protein phosphatase 1 regulatory subunit 27ENSG000001826768
Q8WUF5 / PPP1R13L / protein phosphatase 1 regulatory subunit 13 likeENSG000001048817
NRARP / Q7Z6K4 / NOTCH regulated ankyrin repeat proteinENSG000001984355


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR017417  Protein phosphatase 1, regulatory subunit 16A/B
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IMP
 biological_processGO:0014066 regulation of phosphatidylinositol 3-kinase signaling IMP
 biological_processGO:0035304 regulation of protein dephosphorylation IMP
 biological_processGO:0035307 positive regulation of protein dephosphorylation IDA
 biological_processGO:0035308 negative regulation of protein dephosphorylation IDA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0051489 regulation of filopodium assembly ISS
 biological_processGO:0061028 establishment of endothelial barrier IMP
 biological_processGO:1902309 negative regulation of peptidyl-serine dephosphorylation IMP
 biological_processGO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0042995 cell projection IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019888 protein phosphatase regulator activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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