ENSG00000104881


Homo sapiens

Features
Gene ID: ENSG00000104881
  
Biological name :PPP1R13L
  
Synonyms : PPP1R13L / protein phosphatase 1 regulatory subunit 13 like / Q8WUF5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.32
Gene start: 45379634
Gene end: 45406349
  
Corresponding Affymetrix probe sets: 218849_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466939
Ensembl peptide - ENSP00000466730
Ensembl peptide - ENSP00000467471
Ensembl peptide - ENSP00000354218
Ensembl peptide - ENSP00000403902
Ensembl peptide - ENSP00000466555
NCBI entrez gene - 10848     See in Manteia.
OMIM - 607463
RefSeq - XM_017026178
RefSeq - NM_001142502
RefSeq - NM_006663
RefSeq - XM_017026177
RefSeq Peptide - NP_006654
RefSeq Peptide - NP_001135974
swissprot - A0A024R0Q5
swissprot - K7EML6
swissprot - K7EN03
swissprot - K7EPP1
swissprot - K7ENG6
swissprot - Q8WUF5
Ensembl - ENSG00000104881
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp1r13lENSDARG00000013777Danio rerio
 Q5I1X5ENSMUSG00000040734Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q13625 / TP53BP2 / tumor protein p53 binding protein 2ENSG0000014351431
Q96KQ4 / PPP1R13B / protein phosphatase 1 regulatory subunit 13BENSG0000008880830
O60237 / PPP1R12B / protein phosphatase 1 regulatory subunit 12BENSG0000007715710
Q9BZL4 / PPP1R12C / protein phosphatase 1 regulatory subunit 12CENSG000001255039
O14974 / PPP1R12A / protein phosphatase 1 regulatory subunit 12AENSG000000582728
Q96I34 / PPP1R16A / protein phosphatase 1 regulatory subunit 16AENSG000001609726
Q96T49 / PPP1R16B / protein phosphatase 1 regulatory subunit 16BENSG000001014455
NRARP / Q7Z6K4 / NOTCH regulated ankyrin repeat proteinENSG000001984351
Q86WC6 / PPP1R27 / protein phosphatase 1 regulatory subunit 27ENSG000001826761


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR028320  RelA-associated inhibitor
 IPR036028  SH3-like domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0003215 cardiac right ventricle morphogenesis IEA
 biological_processGO:0003229 ventricular cardiac muscle tissue development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0031076 embryonic camera-type eye development IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0042633 hair cycle IEA
 biological_processGO:0045597 positive regulation of cell differentiation IEA
 biological_processGO:0048871 multicellular organismal homeostasis IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0045171 intercellular bridge IDA
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Association with Co-factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000078900 TP73 / O15350 / tumor protein p73  / complex / reaction
 ENSG00000073282 TP63 / Q9H3D4 / tumor protein p63  / reaction / complex
 ENSG00000141510 TP53 / P04637 / tumor protein p53  / reaction / complex






 

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