ENSMUSG00000037754


Mus musculus

Features
Gene ID: ENSMUSG00000037754
  
Biological name :Ppp1r16b
  
Synonyms : Ppp1r16b / protein phosphatase 1, regulatory (inhibitor) subunit 16B / Q8VHQ3
  
Possible biological names infered from orthology : protein phosphatase 1 regulatory subunit 16B / Q96T49
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 158665398
Gene end: 158766334
  
Corresponding Affymetrix probe sets: 10478145 (MoGene1.0st)   1425414_at (Mouse Genome 430 2.0 Array)   1455080_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039540
Ensembl peptide - ENSMUSP00000062615
Ensembl peptide - ENSMUSP00000099405
Ensembl peptide - ENSMUSP00000117310
NCBI entrez gene - 228852     See in Manteia.
MGI - MGI:2151841
RefSeq - XM_011239493
RefSeq - NM_001159662
RefSeq - NM_153089
RefSeq - XM_011239492
RefSeq Peptide - NP_694729
RefSeq Peptide - NP_001153134
swissprot - Q544H9
swissprot - Q8VHQ3
swissprot - A2AC90
Ensembl - ENSMUSG00000037754
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp1r16bENSDARG00000079860Danio rerio
 PPP1R16BENSGALG00000003568Gallus gallus
 Q96T49ENSG00000101445Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q923M0 / Ppp1r16a / protein phosphatase 1, regulatory (inhibitor) subunit 16A / Q96I34* / protein phosphatase 1 regulatory subunit 16A*ENSMUSG0000003381947
Q8BG95 / Ppp1r12b / protein phosphatase 1, regulatory (inhibitor) subunit 12B / O60237* / protein phosphatase 1 regulatory subunit 12B*ENSMUSG0000007355727
Q3UMT1 / Ppp1r12c / Protein phosphatase 1 regulatory subunit 12C / Q9BZL4*ENSMUSG0000001925426
Q9DBR7 / Ppp1r12a / protein phosphatase 1, regulatory (inhibitor) subunit 12A / O14974* / protein phosphatase 1 regulatory subunit 12A*ENSMUSG0000001990726
Q62415 / Ppp1r13b / protein phosphatase 1, regulatory (inhibitor) subunit 13B / Q96KQ4* / protein phosphatase 1 regulatory subunit 13B*ENSMUSG0000002128514
Trp53bp2 / transformation related protein 53 binding protein 2 / Q13625* / TP53BP2* / tumor protein p53 binding protein 2*ENSMUSG0000002651014
Q9D119 / Ppp1r27 / Protein phosphatase 1 regulatory subunit 27 / Q86WC6*ENSMUSG000000251298
Q5I1X5 / Ppp1r13l / protein phosphatase 1, regulatory (inhibitor) subunit 13 like / Q8WUF5* / protein phosphatase 1 regulatory subunit 13 like*ENSMUSG000000407347
Nrarp / Q91ZA8 / Notch-regulated ankyrin repeat-containing protein / Q7Z6K4* / NOTCH regulated ankyrin repeat protein*ENSMUSG000000782025


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR017417  Protein phosphatase 1, regulatory subunit 16A/B
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001938 positive regulation of endothelial cell proliferation ISO
 biological_processGO:0014066 regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0035304 regulation of protein dephosphorylation ISO
 biological_processGO:0035307 positive regulation of protein dephosphorylation ISO
 biological_processGO:0035308 negative regulation of protein dephosphorylation ISO
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0051489 regulation of filopodium assembly ISS
 biological_processGO:0061028 establishment of endothelial barrier ISO
 biological_processGO:1902309 negative regulation of peptidyl-serine dephosphorylation ISO
 biological_processGO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016607 nuclear speck ISO
 cellular_componentGO:0042995 cell projection ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cacna1smdg/Cacna1smdg
Genetic Background: involves: 129 * STOCK T/t4

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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