ENSG00000101811


Homo sapiens

Features
Gene ID: ENSG00000101811
  
Biological name :CSTF2
  
Synonyms : cleavage stimulation factor subunit 2 / CSTF2 / P33240
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q22.1
Gene start: 100820359
Gene end: 100840932
  
Corresponding Affymetrix probe sets: 204459_at (Human Genome U133 Plus 2.0 Array)   238821_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362063
Ensembl peptide - ENSP00000432060
Ensembl peptide - ENSP00000415705
Ensembl peptide - ENSP00000387996
NCBI entrez gene - 1478     See in Manteia.
OMIM - 300907
RefSeq - NM_001306206
RefSeq - NM_001306209
RefSeq - NM_001325
RefSeq Peptide - NP_001293138
RefSeq Peptide - NP_001316
RefSeq Peptide - NP_001293135
swissprot - P33240
swissprot - E7EWR4
swissprot - A0A0A0MT56
swissprot - E9PID8
Ensembl - ENSG00000101811
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cstf2ENSDARG00000090788Danio rerio
 CSTF2ENSGALG00000006760Gallus gallus
 Cstf2ENSMUSG00000031256Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CSTF2T / Q9H0L4 / cleavage stimulation factor subunit 2 tau variantENSG0000017761371


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR025742  Cleavage stimulation factor subunit 2, hinge domain
 IPR026896  Transcription termination and cleavage factor, C-terminal domain
 IPR033105  Cleavage stimulation factor subunit 2
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006378 mRNA polyadenylation IEA
 biological_processGO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0031124 mRNA 3"-end processing IEA
 biological_processGO:0098789 pre-mRNA cleavage required for polyadenylation IBA
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex IEA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0071920 cleavage body IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
tRNA processing in the nucleus
mRNA Splicing - Major Pathway
mRNA 3-end processing
Processing of Intronless Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000176102 CSTF3 / Q12996 / cleavage stimulation factor subunit 3  / complex
 ENSG00000114503 NCBP2 / P52298 / nuclear cap binding protein subunit 2  / reaction / complex
 ENSG00000101138 CSTF1 / Q05048 / cleavage stimulation factor subunit 1  / complex
 ENSG00000136937 NCBP1 / Q09161 / nuclear cap binding protein subunit 1  / complex / reaction






 

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