ENSG00000105143


Homo sapiens

Features
Gene ID: ENSG00000105143
  
Biological name :SLC1A6
  
Synonyms : P48664 / SLC1A6 / solute carrier family 1 member 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.12
Gene start: 14950034
Gene end: 15022990
  
Corresponding Affymetrix probe sets: 1554592_a_at (Human Genome U133 Plus 2.0 Array)   1554593_s_at (Human Genome U133 Plus 2.0 Array)   206882_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000472133
Ensembl peptide - ENSP00000471781
Ensembl peptide - ENSP00000472837
Ensembl peptide - ENSP00000221742
Ensembl peptide - ENSP00000409386
Ensembl peptide - ENSP00000446175
Ensembl peptide - ENSP00000469551
Ensembl peptide - ENSP00000471038
Ensembl peptide - ENSP00000471129
Ensembl peptide - ENSP00000471562
NCBI entrez gene - 6511     See in Manteia.
OMIM - 600637
RefSeq - XM_017027152
RefSeq - NM_001272087
RefSeq - NM_001272088
RefSeq - NM_005071
RefSeq - XM_006722842
RefSeq - XM_006722844
RefSeq Peptide - NP_001259017
RefSeq Peptide - NP_005062
RefSeq Peptide - NP_001259016
swissprot - M0QY32
swissprot - M0R063
swissprot - M0R0B5
swissprot - M0R106
swissprot - M0R2V7
swissprot - M0R1V3
swissprot - P48664
swissprot - E7EV13
Ensembl - ENSG00000105143
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc1a6ENSDARG00000010096Danio rerio
 SLC1A6ENSGALG00000000558Gallus gallus
 O35544ENSMUSG00000005357Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P43003 / SLC1A3 / solute carrier family 1 member 3ENSG0000007921566
O00341 / SLC1A7 / solute carrier family 1 member 7ENSG0000016238347
P43005 / SLC1A1 / solute carrier family 1 member 1ENSG0000010668846
P43004 / SLC1A2 / solute carrier family 1 member 2ENSG0000011043644
P43007 / SLC1A4 / solute carrier family 1 member 4ENSG0000011590241
Q15758 / SLC1A5 / solute carrier family 1 member 5ENSG0000010528139


Protein motifs (from Interpro)
Interpro ID Name
 IPR001991  Sodium:dicarboxylate symporter
 IPR018107  Sodium:dicarboxylate symporter, conserved site
 IPR036458  Sodium:dicarboxylate symporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport TAS
 biological_processGO:0006865 amino acid transport IEA
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0014047 glutamate secretion TAS
 biological_processGO:0015810 aspartate transmembrane transport TAS
 biological_processGO:0015813 L-glutamate transmembrane transport TAS
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070778 L-aspartate transmembrane transport IEA
 biological_processGO:0098712 L-glutamate import across plasma membrane ISS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IDA
 molecular_functionGO:0005313 L-glutamate transmembrane transporter activity IEA
 molecular_functionGO:0005314 high-affinity glutamate transmembrane transporter activity ISS
 molecular_functionGO:0015171 amino acid transmembrane transporter activity TAS
 molecular_functionGO:0015183 L-aspartate transmembrane transporter activity TAS
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glutamate Neurotransmitter Release Cycle
Transport of inorganic cations/anions and amino acids/oligopeptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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