Manteia

ENSMUSG00000005357

Mus musculus

Features

Gene ID:	ENSMUSG00000005357

Biological name :	Slc1a6

Synonyms :	O35544 / Slc1a6 / solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6

Possible biological names infered from orthology :	P48664 / solute carrier family 1 member 6

Species:	Mus musculus

Chr. number:	10
Strand:	1
Band:	C1
Gene start:	78780496
Gene end:	78814765

Corresponding Affymetrix probe sets:	10364402 (MoGene1.0st) 1418933_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000005490 Ensembl peptide - ENSMUSP00000151544 NCBI entrez gene - 20513 See in Manteia. MGI - MGI:1096331 RefSeq - XM_006513422 RefSeq - XM_006513424 RefSeq - NM_009200 RefSeq Peptide - NP_033226 swissprot - O35544 swissprot - B2RQX4 swissprot - A0A1W2P762 Ensembl - ENSMUSG00000005357

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
P56564 / Slc1a3 / solute carrier family 1 (glial high affinity glutamate transporter), member 3 / P43003* / solute carrier family 1 member 3*	ENSMUSG00000005360	66
P51906 / Slc1a1 / solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 / P43005* / solute carrier family 1 member 1*	ENSMUSG00000024935	47
Slc1a7 / solute carrier family 1 (glutamate transporter), member 7 / O00341* / solute carrier family 1 member 7*	ENSMUSG00000008932	47
P43006 / Slc1a2 / solute carrier family 1 (glial high affinity glutamate transporter), member 2 / P43004* / solute carrier family 1 member 2*	ENSMUSG00000005089	43
O35874 / Slc1a4 / solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 / P43007* / solute carrier family 1 member 4*	ENSMUSG00000020142	40
Slc1a5 / solute carrier family 1 (neutral amino acid transporter), member 5 / Q15758* / solute carrier family 1 member 5*	ENSMUSG00000001918	39

Protein motifs (from Interpro)

Interpro ID	Name
IPR001991	Sodium:dicarboxylate symporter
IPR018107	Sodium:dicarboxylate symporter, conserved site
IPR036458	Sodium:dicarboxylate symporter superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006865	amino acid transport	IEA
biological_process	GO:0015813	L-glutamate transmembrane transport	IMP
biological_process	GO:0042391	regulation of membrane potential	IMP
biological_process	GO:0055085	transmembrane transport	IEA
biological_process	GO:0098712	L-glutamate import across plasma membrane	ISS
cellular_component	GO:0005794	Golgi apparatus	IDA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0005887	integral component of plasma membrane	ISS
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0045111	intermediate filament cytoskeleton	IEA
molecular_function	GO:0005313	L-glutamate transmembrane transporter activity	IMP
molecular_function	GO:0005314	high-affinity glutamate transmembrane transporter activity	ISS
molecular_function	GO:0015293	symporter activity	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Glutamate Neurotransmitter Release Cycle

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0005403	abnormal nerve conduction	"anomaly in the act of transmitting electricity along a single nerve" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ift172^wim/Del(5D5Mit73-D5Mit351)5Jcs Genetic Background: involves: 129S4/SvJae * C3HeB/FeJ * C57BL/6J

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr