ENSG00000111247


Homo sapiens

Features
Gene ID: ENSG00000111247
  
Biological name :RAD51AP1
  
Synonyms : Q96B01 / RAD51AP1 / RAD51 associated protein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.32
Gene start: 4538798
Gene end: 4560048
  
Corresponding Affymetrix probe sets: 204146_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000446002
Ensembl peptide - ENSP00000446296
Ensembl peptide - ENSP00000228843
Ensembl peptide - ENSP00000309479
Ensembl peptide - ENSP00000399859
Ensembl peptide - ENSP00000438172
Ensembl peptide - ENSP00000438422
Ensembl peptide - ENSP00000439019
Ensembl peptide - ENSP00000439925
Ensembl peptide - ENSP00000442890
Ensembl peptide - ENSP00000443837
Ensembl peptide - ENSP00000444769
NCBI entrez gene - 10635     See in Manteia.
OMIM - 603070
RefSeq - NM_001130862
RefSeq - NM_006479
RefSeq Peptide - NP_001124334
RefSeq Peptide - NP_006470
swissprot - H0YFK6
swissprot - H0YGT5
swissprot - Q96B01
swissprot - F5H031
swissprot - F5H1Y0
swissprot - F5H4V6
swissprot - F5H710
Ensembl - ENSG00000111247
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rad51ap1ENSDARG00000045853Danio rerio
 RAD51AP1ENSGALG00000017290Gallus gallus
 Rad51ap1ENSMUSG00000030346Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026632  RAD51-associated protein 1
 IPR031419  RAD51 interacting motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0000731 DNA synthesis involved in DNA repair TAS
 biological_processGO:0000732 strand displacement TAS
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IDA
 biological_processGO:0036297 interstrand cross-link repair IMP
 biological_processGO:0071479 cellular response to ionizing radiation IDA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0032991 protein-containing complex IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000083093 PALB2 / Q86YC2 / partner and localizer of BRCA2  / reaction / complex
 ENSG00000051180 RAD51 / Q06609 / RAD51 recombinase  / complex
 ENSG00000139618 BRCA2 / P51587 / BRCA2, DNA repair associated  / complex
 ENSG00000138376 BARD1 / Q99728 / BRCA1 associated RING domain 1  / complex
 ENSG00000108384 O43502 / RAD51C / RAD51 paralog C  / reaction
 ENSG00000185379 O75771 / RAD51D / RAD51 paralog D  / reaction
 ENSG00000101773 RBBP8 / Q99708 / RB binding protein 8, endonuclease  / complex
 ENSG00000012048 BRCA1 / P38398 / BRCA1, DNA repair associated  / complex
 ENSG00000196584 XRCC2 / O43543 / X-ray repair cross complementing 2  / reaction
 ENSG00000182185 O15315 / RAD51B / RAD51 paralog B  / reaction






 

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