ENSMUSG00000030346


Mus musculus

Features
Gene ID: ENSMUSG00000030346
  
Biological name :Rad51ap1
  
Synonyms : Rad51ap1 / RAD51-associated protein 1 isoform 2
  
Possible biological names infered from orthology : Q96B01 / RAD51 associated protein 1
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: F3
Gene start: 126923050
Gene end: 126939587
  
Corresponding Affymetrix probe sets: 10548086 (MoGene1.0st)   1417938_at (Mouse Genome 430 2.0 Array)   1417939_at (Mouse Genome 430 2.0 Array)   1417940_s_at (Mouse Genome 430 2.0 Array)   1448899_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000107839
Ensembl peptide - ENSMUSP00000144327
Ensembl peptide - ENSMUSP00000122978
Ensembl peptide - ENSMUSP00000107841
NCBI entrez gene - 19362     See in Manteia.
MGI - MGI:1098224
RefSeq - XM_006505763
RefSeq - NM_009013
RefSeq Peptide - NP_001334384
RefSeq Peptide - NP_033039
swissprot - A0A0J9YUS9
swissprot - A0A0R4J1H1
swissprot - D3Z7I5
swissprot - A0A0R4J1G4
Ensembl - ENSMUSG00000030346
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rad51ap1ENSDARG00000045853Danio rerio
 RAD51AP1ENSGALG00000017290Gallus gallus
 Q96B01ENSG00000111247Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026632  RAD51-associated protein 1
 IPR031419  RAD51 interacting motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IEA
 biological_processGO:0036297 interstrand cross-link repair IEA
 biological_processGO:0071479 cellular response to ionizing radiation IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA


Pathways (from Reactome)
Pathway description
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000017146 Brca1 / P48754 / Breast cancer type 1 susceptibility protein homolog / P38398* / BRCA1, DNA repair associated*  / complex
 ENSMUSG00000026196 Bard1 / O70445 / BRCA1-associated RING domain protein 1 / Q99728* / BRCA1 associated RING domain 1*  / complex
 ENSMUSG00000041238 Rbbp8 / Q80YR6 / retinoblastoma binding protein 8, endonuclease / Q99708* / RB binding protein 8, endonuclease*  / complex
 ENSMUSG00000044702 Palb2 / Q3U0P1 / Partner and localizer of BRCA2 / Q86YC2*  / complex / reaction
 ENSMUSG00000041147 Brca2 / P97929 / Breast cancer type 2 susceptibility protein homolog / P51587* / BRCA2, DNA repair associated*  / complex
 ENSMUSG00000018841 O55230 / Rad51d / RAD51 paralog D / O75771*  / reaction
 ENSMUSG00000007646 Q924H5 / Rad51c / DNA repair 3 / O43502* / RAD51 paralog C*  / reaction
 ENSMUSG00000059060 O35719 / Rad51b / DNA repair 2 / O15315* / RAD51 paralog B*  / reaction
 ENSMUSG00000028933 Xrcc2 / Q9CX47 / X-ray repair complementing defective repair in Chinese hamster cells 2 / O43543* / X-ray repair cross complementing 2*  / reaction






 

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