ENSG00000113088


Homo sapiens

Features
Gene ID: ENSG00000113088
  
Biological name :GZMK
  
Synonyms : granzyme K / GZMK / P49863
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q11.2
Gene start: 55024253
Gene end: 55034570
  
Corresponding Affymetrix probe sets: 206666_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000231009
NCBI entrez gene - 3003     See in Manteia.
OMIM - 600784
RefSeq - NM_002104
RefSeq Peptide - NP_002095
swissprot - P49863
Ensembl - ENSG00000113088
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gzmaENSDARG00000090380Danio rerio
 gzmkENSDARG00000028780Danio rerio
 GzmkENSMUSG00000042385Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GZMA / P12544 / granzyme AENSG0000014564939
CFD / P00746 / complement factor DENSG0000019776638
GZMB / P10144 / granzyme BENSG0000010045335
GZMH / P20718 / granzyme HENSG0000010045034
GZMM / P51124 / granzyme MENSG0000019754034
CTSG / P08311 / cathepsin GENSG0000010044834
CMA1 / P23946 / chymase 1ENSG0000009200933
PRSS57 / Q6UWY2 / serine protease 57ENSG0000018519833


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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