ENSG00000185198


Homo sapiens

Features
Gene ID: ENSG00000185198
  
Biological name :PRSS57
  
Synonyms : PRSS57 / Q6UWY2 / serine protease 57
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 685546
Gene end: 695498
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000482358
Ensembl peptide - ENSP00000327386
NCBI entrez gene - 400668     See in Manteia.
RefSeq - NM_001308209
RefSeq - NM_214710
RefSeq Peptide - NP_001295138
RefSeq Peptide - NP_999875
swissprot - Q6UWY2
swissprot - A0A0A0MR61
Ensembl - ENSG00000185198
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-21e2.13ENSDARG00000094840Danio rerio
 PRSS57ENSGALG00000035762Gallus gallus
 Prss57ENSMUSG00000020323Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GZMM / P51124 / granzyme MENSG0000019754036
GZMB / P10144 / granzyme BENSG0000010045334
CFD / P00746 / complement factor DENSG0000019776634
GZMH / P20718 / granzyme HENSG0000010045034
CTSG / P08311 / cathepsin GENSG0000010044834
CMA1 / P23946 / chymase 1ENSG0000009200933
GZMK / P49863 / granzyme KENSG0000011308831
GZMA / P12544 / granzyme AENSG0000014564929


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0035578 azurophil granule lumen IDA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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