ENSG00000113504


Homo sapiens

Features
Gene ID: ENSG00000113504
  
Biological name :SLC12A7
  
Synonyms : Q9Y666 / SLC12A7 / solute carrier family 12 member 7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: p15.33
Gene start: 1050376
Gene end: 1112035
  
Corresponding Affymetrix probe sets: 218066_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000489272
Ensembl peptide - ENSP00000489285
Ensembl peptide - ENSP00000264930
Ensembl peptide - ENSP00000428854
NCBI entrez gene - 10723     See in Manteia.
OMIM - 604879
RefSeq - XM_017008959
RefSeq - XM_005248231
RefSeq - XM_011513939
RefSeq - XM_011513940
RefSeq - XM_011513941
RefSeq - XM_017008958
RefSeq - NM_006598
RefSeq Peptide - NP_006589
swissprot - A0A0U1RR18
swissprot - H0YB78
swissprot - A0A0U1RR10
swissprot - Q9Y666
Ensembl - ENSG00000113504
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc12a7aENSDARG00000073756Danio rerio
 slc12a7bENSDARG00000062058Danio rerio
 SLC12A7ENSGALG00000042396Gallus gallus
 Q9WVL3ENSMUSG00000017756Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H2X9 / SLC12A5 / solute carrier family 12 member 5ENSG0000012414073
Q9UHW9 / SLC12A6 / solute carrier family 12 member 6ENSG0000014019970
Q9UP95 / SLC12A4 / solute carrier family 12 member 4ENSG0000012406768
P55011 / SLC12A2 / solute carrier family 12 member 2ENSG0000006465127
Q13621 / SLC12A1 / solute carrier family 12 member 1ENSG0000007480326
P55017 / SLC12A3 / solute carrier family 12 member 3ENSG0000007091524
Q9BXP2 / SLC12A9 / solute carrier family 12 member 9ENSG0000014682821
A0AV02 / SLC12A8 / solute carrier family 12 member 8ENSG0000022195515


Protein motifs (from Interpro)
Interpro ID Name
 IPR000076  K/Cl co-transporter
 IPR004841  Amino acid permease/ SLC12A domain
 IPR004842  SLC12A transporter family
 IPR018491  SLC12A transporter, C-terminal
 IPR030354  K/Cl co-transporter 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006884 cell volume homeostasis IEA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0015377 cation:chloride symporter activity IEA
 molecular_functionGO:0015379 potassium:chloride symporter activity IEA
 molecular_functionGO:0019901 protein kinase binding IPI


Pathways (from Reactome)
Pathway description
Cation-coupled Chloride cotransporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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