ENSG00000116128


Homo sapiens

Features
Gene ID: ENSG00000116128
  
Biological name :BCL9
  
Synonyms : B cell CLL/lymphoma 9 / BCL9 / O00512
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.2
Gene start: 147541412
Gene end: 147626216
  
Corresponding Affymetrix probe sets: 204129_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000234739
NCBI entrez gene - 607     See in Manteia.
OMIM - 602597
RefSeq - XM_017002026
RefSeq - NM_004326
RefSeq - XM_005272971
RefSeq - XM_005277417
RefSeq - XM_005277418
RefSeq Peptide - NP_004317
swissprot - O00512
swissprot - A0A024QYY4
Ensembl - ENSG00000116128
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bcl9ENSDARG00000036687Danio rerio
 BCL9ENSGALG00000037655Gallus gallus
 Bcl9ENSMUSG00000038256Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BCL9L / Q86UU0 / B cell CLL/lymphoma 9 likeENSG0000018617436


Protein motifs (from Interpro)
Interpro ID Name
 IPR015668  B Cell Lymphoma 9
 IPR024670  B-cell lymphoma 9, beta-catenin binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0014908 myotube differentiation involved in skeletal muscle regeneration IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:1904837 beta-catenin-TCF complex assembly TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005801 cis-Golgi network IDA
 cellular_componentGO:1990907 beta-catenin-TCF complex IPI
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding IEA


Pathways (from Reactome)
Pathway description
Formation of the beta-catenin:TCF transactivating complex
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000138795 LEF1 / Q9UJU2 / lymphoid enhancer binding factor 1  / reaction / complex
 ENSG00000171016 PYGO1 / Q9Y3Y4 / pygopus family PHD finger 1  / reaction / complex
 ENSG00000148737 Q9NQB0 / TCF7L2 / transcription factor 7 like 2  / complex / reaction
 ENSG00000168036 CTNNB1 / P35222 / catenin beta 1  / reaction / complex
 ENSG00000163348 PYGO2 / Q9BRQ0 / pygopus family PHD finger 2  / reaction / complex






 

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