ENSG00000171016


Homo sapiens

Features
Gene ID: ENSG00000171016
  
Biological name :PYGO1
  
Synonyms : PYGO1 / pygopus family PHD finger 1 / Q9Y3Y4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q21.3
Gene start: 55538890
Gene end: 55588947
  
Corresponding Affymetrix probe sets: 215517_at (Human Genome U133 Plus 2.0 Array)   215520_at (Human Genome U133 Plus 2.0 Array)   239741_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302327
Ensembl peptide - ENSP00000457777
Ensembl peptide - ENSP00000496139
NCBI entrez gene - 26108     See in Manteia.
OMIM - 606902
RefSeq - XM_011521446
RefSeq - NM_015617
RefSeq - XM_005254300
RefSeq Peptide - NP_001317255
RefSeq Peptide - NP_056432
swissprot - Q9Y3Y4
Ensembl - ENSG00000171016
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pygo1ENSDARG00000098687Danio rerio
 PYGO1ENSGALG00000004369Gallus gallus
 Pygo1ENSMUSG00000034910Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PYGO2 / Q9BRQ0 / pygopus family PHD finger 2ENSG0000016334835


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0007286 spermatid development IEA
 biological_processGO:0007289 spermatid nucleus differentiation IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0034504 protein localization to nucleus IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:1904837 beta-catenin-TCF complex assembly TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035064 methylated histone binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Formation of the beta-catenin:TCF transactivating complex
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000138795 LEF1 / Q9UJU2 / lymphoid enhancer binding factor 1  / complex / reaction
 ENSG00000116128 BCL9 / O00512 / B cell CLL/lymphoma 9  / reaction / complex
 ENSG00000186174 BCL9L / Q86UU0 / B cell CLL/lymphoma 9 like  / reaction / complex
 ENSG00000148737 Q9NQB0 / TCF7L2 / transcription factor 7 like 2  / reaction / complex
 ENSG00000168036 CTNNB1 / P35222 / catenin beta 1  / complex / reaction






 

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