ENSG00000186174


Homo sapiens

Features
Gene ID: ENSG00000186174
  
Biological name :BCL9L
  
Synonyms : B cell CLL/lymphoma 9 like / BCL9L / Q86UU0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q23.3
Gene start: 118893875
Gene end: 118925608
  
Corresponding Affymetrix probe sets: 227616_at (Human Genome U133 Plus 2.0 Array)   228065_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432804
Ensembl peptide - ENSP00000482938
Ensembl peptide - ENSP00000335320
NCBI entrez gene - 283149     See in Manteia.
OMIM - 609004
RefSeq - XM_017017574
RefSeq - XM_006718815
RefSeq - XM_011542756
RefSeq - XM_017017572
RefSeq - XM_017017573
RefSeq - NM_182557
RefSeq - XM_005271511
RefSeq - XM_005271512
RefSeq - XM_005271513
RefSeq Peptide - NP_872363
swissprot - E9PNR0
swissprot - A0A087WZX0
swissprot - Q86UU0
Ensembl - ENSG00000186174
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bcl9lENSDARG00000055054Danio rerio
 BCL9LENSGALG00000007685Gallus gallus
 Bcl9lENSMUSG00000063382Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BCL9 / O00512 / B cell CLL/lymphoma 9ENSG0000011612834


Protein motifs (from Interpro)
Interpro ID Name
 IPR015668  B Cell Lymphoma 9
 IPR024670  B-cell lymphoma 9, beta-catenin binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0022604 regulation of cell morphogenesis IMP
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:1903506 regulation of nucleic acid-templated transcription IEA
 biological_processGO:1904837 beta-catenin-TCF complex assembly TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:1990907 beta-catenin-TCF complex IDA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0008013 beta-catenin binding IEA


Pathways (from Reactome)
Pathway description
Formation of the beta-catenin:TCF transactivating complex
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000138795 LEF1 / Q9UJU2 / lymphoid enhancer binding factor 1  / reaction / complex
 ENSG00000171016 PYGO1 / Q9Y3Y4 / pygopus family PHD finger 1  / reaction / complex
 ENSG00000148737 Q9NQB0 / TCF7L2 / transcription factor 7 like 2  / complex / reaction
 ENSG00000168036 CTNNB1 / P35222 / catenin beta 1  / reaction / complex
 ENSG00000163348 PYGO2 / Q9BRQ0 / pygopus family PHD finger 2  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr