ENSG00000116350


Homo sapiens

Features
Gene ID: ENSG00000116350
  
Biological name :SRSF4
  
Synonyms : Q08170 / serine and arginine rich splicing factor 4 / SRSF4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p35.3
Gene start: 29147743
Gene end: 29181987
  
Corresponding Affymetrix probe sets: 201696_at (Human Genome U133 Plus 2.0 Array)   239511_s_at (Human Genome U133 Plus 2.0 Array)   239512_at (Human Genome U133 Plus 2.0 Array)   241245_at (Human Genome U133 Plus 2.0 Array)   242837_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473728
Ensembl peptide - ENSP00000487379
Ensembl peptide - ENSP00000485813
Ensembl peptide - ENSP00000362900
NCBI entrez gene - 6429     See in Manteia.
OMIM - 601940
RefSeq - NM_005626
RefSeq - XM_011541951
RefSeq Peptide - NP_005617
swissprot - A0A0D9SGD2
swissprot - Q08170
swissprot - S4R2X6
swissprot - A0A0D9SEM4
Ensembl - ENSG00000116350
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srsf4ENSDARG00000105293Danio rerio
 ENSGALG00000037539Gallus gallus
 Srsf4ENSMUSG00000028911Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SRSF6 / Q13247 / serine and arginine rich splicing factor 6ENSG0000012419350
SRSF5 / Q13243 / serine and arginine rich splicing factor 5ENSG0000010065034
SRSF1 / Q07955 / serine and arginine rich splicing factor 1ENSG0000013645024
SRSF9 / Q13242 / serine and arginine rich splicing factor 9ENSG0000011178618


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR035585  Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000375 RNA splicing, via transesterification reactions TAS
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:1990825 sequence-specific mRNA binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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