ENSG00000124193


Homo sapiens

Features
Gene ID: ENSG00000124193
  
Biological name :SRSF6
  
Synonyms : Q13247 / serine and arginine rich splicing factor 6 / SRSF6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.11
Gene start: 43457928
Gene end: 43464247
  
Corresponding Affymetrix probe sets: 206108_s_at (Human Genome U133 Plus 2.0 Array)   208804_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433544
Ensembl peptide - ENSP00000244020
NCBI entrez gene - 6431     See in Manteia.
OMIM - 601944
RefSeq - NM_006275
RefSeq Peptide - NP_006266
swissprot - Q13247
Ensembl - ENSG00000124193
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srsf6aENSDARG00000013729Danio rerio
 srsf6bENSDARG00000016783Danio rerio
 SRSF6ENSGALG00000000990Gallus gallus
 Srsf6ENSMUSG00000016921Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SRSF4 / Q08170 / serine and arginine rich splicing factor 4ENSG0000011635071
SRSF5 / Q13243 / serine and arginine rich splicing factor 5ENSG0000010065051
SRSF1 / Q07955 / serine and arginine rich splicing factor 1ENSG0000013645033
SRSF9 / Q13242 / serine and arginine rich splicing factor 9ENSG0000011178626


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR034511  SRSF6, RNA recognition motif 1
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000380 alternative mRNA splicing, via spliceosome IDA
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IDA
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006376 mRNA splice site selection TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010837 regulation of keratinocyte proliferation IMP
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0045617 negative regulation of keratinocyte differentiation IMP
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IDA
 biological_processGO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis IDA
 biological_processGO:0060548 negative regulation of cell death IDA
 biological_processGO:0061041 regulation of wound healing IMP
 biological_processGO:2000675 negative regulation of type B pancreatic cell apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0036002 pre-mRNA binding IDA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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