ENSG00000100650


Homo sapiens

Features
Gene ID: ENSG00000100650
  
Biological name :SRSF5
  
Synonyms : Q13243 / serine and arginine rich splicing factor 5 / SRSF5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.1
Gene start: 69726900
Gene end: 69772005
  
Corresponding Affymetrix probe sets: 203380_x_at (Human Genome U133 Plus 2.0 Array)   210077_s_at (Human Genome U133 Plus 2.0 Array)   212266_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452090
Ensembl peptide - ENSP00000452123
Ensembl peptide - ENSP00000474409
Ensembl peptide - ENSP00000452449
Ensembl peptide - ENSP00000452400
Ensembl peptide - ENSP00000377892
Ensembl peptide - ENSP00000450918
Ensembl peptide - ENSP00000451088
Ensembl peptide - ENSP00000451391
NCBI entrez gene - 6430     See in Manteia.
OMIM - 600914
RefSeq - XM_005267999
RefSeq - XM_017021593
RefSeq - XM_011537077
RefSeq - XM_005268000
RefSeq - NM_001039465
RefSeq - NM_001320214
RefSeq - NM_006925
RefSeq Peptide - NP_001034554
RefSeq Peptide - NP_001307143
RefSeq Peptide - NP_008856
swissprot - Q13243
swissprot - B4DUA4
swissprot - G3V5K8
swissprot - A0A024R6D8
swissprot - B4DJK0
Ensembl - ENSG00000100650
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srsf5bENSDARG00000027734Danio rerio
 SRSF5ENSGALG00000009421Gallus gallus
 Srsf5ENSMUSG00000021134Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SRSF6 / Q13247 / serine and arginine rich splicing factor 6ENSG0000012419364
SRSF4 / Q08170 / serine and arginine rich splicing factor 4ENSG0000011635062
SRSF1 / Q07955 / serine and arginine rich splicing factor 1ENSG0000013645039
SRSF9 / Q13242 / serine and arginine rich splicing factor 9ENSG0000011178629


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR035585  Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006376 mRNA splice site selection TAS
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0033120 positive regulation of RNA splicing IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0097421 liver regeneration IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016607 nuclear speck ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043422 protein kinase B binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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