Manteia

ENSMUSG00000016921

Mus musculus

Features

Gene ID:	ENSMUSG00000016921

Biological name :	Srsf6

Synonyms :	Q3TWW8 / serine/arginine-rich splicing factor 6 / Srsf6

Possible biological names infered from orthology :	Q13247 / serine and arginine rich splicing factor 6

Species:	Mus musculus

Chr. number:	2
Strand:	1
Band:	H2
Gene start:	162931528
Gene end:	162937121

Corresponding Affymetrix probe sets:	10478291 (MoGene1.0st) 1416720_at (Mouse Genome 430 2.0 Array) 1416721_s_at (Mouse Genome 430 2.0 Array) 1447898_s_at (Mouse Genome 430 2.0 Array) 1448454_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000141349 Ensembl peptide - ENSMUSP00000142183 Ensembl peptide - ENSMUSP00000119065 NCBI entrez gene - 67996 See in Manteia. MGI - MGI:1915246 RefSeq - NM_026499 RefSeq Peptide - NP_080775 swissprot - A0A0A6YXX6 swissprot - Q3TWW8 Ensembl - ENSMUSG00000016921

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Srsf4 / serine/arginine-rich splicing factor 4 / Q08170* / serine and arginine rich splicing factor 4*	ENSMUSG00000028911	68
Srsf5 / O35326 / serine/arginine-rich splicing factor 5 / Q13243* / serine and arginine rich splicing factor 5*	ENSMUSG00000021134	51
Srsf1 / Q6PDM2 / Serine/arginine-rich splicing factor 1 / Q07955* / serine and arginine rich splicing factor 1*	ENSMUSG00000018379	34
Srsf9 / Q9D0B0 / Serine/arginine-rich splicing factor 9 / Q13242* / serine and arginine rich splicing factor 9*	ENSMUSG00000029538	27

Protein motifs (from Interpro)

Interpro ID	Name
IPR000504	RNA recognition motif domain
IPR034511	SRSF6, RNA recognition motif 1
IPR035979	RNA-binding domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000380	alternative mRNA splicing, via spliceosome	IEA
biological_process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IEA
biological_process	GO:0006376	mRNA splice site selection	IEA
biological_process	GO:0006397	mRNA processing	IEA
biological_process	GO:0008380	RNA splicing	IEA
biological_process	GO:0010629	negative regulation of gene expression	IEA
biological_process	GO:0010837	regulation of keratinocyte proliferation	IEA
biological_process	GO:0032868	response to insulin	IEA
biological_process	GO:0045617	negative regulation of keratinocyte differentiation	IEA
biological_process	GO:0048025	negative regulation of mRNA splicing, via spliceosome	IEA
biological_process	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	IEA
biological_process	GO:0060548	negative regulation of cell death	IEA
biological_process	GO:0061041	regulation of wound healing	IEA
biological_process	GO:2000675	negative regulation of type B pancreatic cell apoptotic process	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0016607	nuclear speck	ISO
molecular_function	GO:0003676	nucleic acid binding	IEA
molecular_function	GO:0003723	RNA binding	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0036002	pre-mRNA binding	IEA

Pathways (from Reactome)

Pathway description

Cleavage of Growing Transcript in the Termination Region

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr