ENSMUSG00000028911


Mus musculus

Features
Gene ID: ENSMUSG00000028911
  
Biological name :Srsf4
  
Synonyms : serine/arginine-rich splicing factor 4 / Srsf4
  
Possible biological names infered from orthology : Q08170 / serine and arginine rich splicing factor 4
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D2.3
Gene start: 131873617
Gene end: 131901706
  
Corresponding Affymetrix probe sets: 10508697 (MoGene1.0st)   1448778_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141468
Ensembl peptide - ENSMUSP00000142148
Ensembl peptide - ENSMUSP00000061474
NCBI entrez gene - 57317     See in Manteia.
MGI - MGI:1890577
RefSeq - XM_017320333
RefSeq - XM_017320334
RefSeq - XM_017320335
RefSeq - NM_020587
RefSeq Peptide - NP_065612
swissprot - Q542V3
swissprot - A0A0A6YWA5
swissprot - A0A0A6YXU8
Ensembl - ENSMUSG00000028911
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srsf4ENSDARG00000105293Danio rerio
 ENSGALG00000037539Gallus gallus
 SRSF4ENSG00000116350Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Srsf6 / Q3TWW8 / serine/arginine-rich splicing factor 6 / Q13247* / serine and arginine rich splicing factor 6*ENSMUSG0000001692147
Srsf5 / O35326 / serine/arginine-rich splicing factor 5 / Q13243* / serine and arginine rich splicing factor 5*ENSMUSG0000002113433
Srsf1 / Q6PDM2 / Serine/arginine-rich splicing factor 1 / Q07955* / serine and arginine rich splicing factor 1*ENSMUSG0000001837924
Srsf9 / Q9D0B0 / Serine/arginine-rich splicing factor 9 / Q13242* / serine and arginine rich splicing factor 9*ENSMUSG0000002953818


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR035585  Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:1990825 sequence-specific mRNA binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002075 abnormal coat color "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Spns2tm1a(KOMP)Wtsi/Wtsi

 MP:0005553 increased circulating creatinine level "greater than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
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Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1+
Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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