ENSG00000117152


Homo sapiens

Features
Gene ID: ENSG00000117152
  
Biological name :RGS4
  
Synonyms : P49798 / regulator of G protein signaling 4 / RGS4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.3
Gene start: 163068775
Gene end: 163076802
  
Corresponding Affymetrix probe sets: 204337_at (Human Genome U133 Plus 2.0 Array)   204338_s_at (Human Genome U133 Plus 2.0 Array)   204339_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356885
Ensembl peptide - ENSP00000436106
Ensembl peptide - ENSP00000433261
Ensembl peptide - ENSP00000432194
Ensembl peptide - ENSP00000397181
Ensembl peptide - ENSP00000356882
Ensembl peptide - ENSP00000356884
NCBI entrez gene - 5999     See in Manteia.
OMIM - 602516
RefSeq - NM_001113380
RefSeq - NM_001113381
RefSeq - NM_005613
RefSeq - NM_001102445
RefSeq Peptide - NP_001095915
RefSeq Peptide - NP_001106852
RefSeq Peptide - NP_005604
RefSeq Peptide - NP_001106851
swissprot - P49798
swissprot - E9PR32
swissprot - A0A024R909
swissprot - E9PS05
Ensembl - ENSG00000117152
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgs4ENSDARG00000070047Danio rerio
 RGS4ENSGALG00000002564Gallus gallus
 Rgs4ENSMUSG00000038530Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGS3 / P49796 / regulator of G protein signaling 3ENSG0000013883536
RGS16 / O15492 / regulator of G protein signaling 16ENSG0000014333331
RGS5 / O15539 / regulator of G protein signaling 5ENSG0000014324831
RGS8 / P57771 / regulator of G protein signaling 8ENSG0000013582431
RGS2 / P41220 / regulator of G protein signaling 2ENSG0000011674127
RGS18 / Q9NS28 / regulator of G protein signaling 18ENSG0000015068127
RGS1 / Q08116 / regulator of G protein signaling 1ENSG0000009010426
RGS20 / O76081 / regulator of G protein signaling 20ENSG0000014750925
RGS21 / Q2M5E4 / regulator of G protein signaling 21ENSG0000025314823
RGS13 / O14921 / regulator of G protein signaling 13ENSG0000012707423
RGS19 / P49795 / regulator of G protein signaling 19ENSG0000017170022
RGS17 / Q9UGC6 / regulator of G protein signaling 17ENSG0000009184419


Protein motifs (from Interpro)
Interpro ID Name
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR034952  Regulator of G-protein signalling 4
 IPR034953  Regulator of G-protein signalling 4, RGS domain
 IPR036305  RGS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway TAS
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0001965 G-protein alpha-subunit binding IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005516 calmodulin binding TAS


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
G alpha (z) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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