ENSG00000135824


Homo sapiens

Features
Gene ID: ENSG00000135824
  
Biological name :RGS8
  
Synonyms : P57771 / regulator of G protein signaling 8 / RGS8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q25.3
Gene start: 182641816
Gene end: 182684576
  
Corresponding Affymetrix probe sets: 224390_s_at (Human Genome U133 Plus 2.0 Array)   234297_at (Human Genome U133 Plus 2.0 Array)   244675_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258302
Ensembl peptide - ENSP00000356528
Ensembl peptide - ENSP00000426289
Ensembl peptide - ENSP00000427076
Ensembl peptide - ENSP00000356527
NCBI entrez gene - 85397     See in Manteia.
OMIM - 607189
RefSeq - XM_017002637
RefSeq - NM_001102450
RefSeq - NM_033345
RefSeq - XM_017002633
RefSeq - XM_017002634
RefSeq - XM_017002635
RefSeq - XM_017002636
RefSeq - XM_005245555
RefSeq - XM_011510089
RefSeq - XM_011510090
RefSeq - XM_011510091
RefSeq - XM_017002631
RefSeq - XM_017002632
RefSeq Peptide - NP_001095920
RefSeq Peptide - NP_203131
swissprot - P57771
swissprot - D6RD36
Ensembl - ENSG00000135824
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgs8ENSDARG00000070037Danio rerio
 RGS8ENSGALG00000026263Gallus gallus
 Rgs8ENSMUSG00000042671Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGS16 / O15492 / regulator of G protein signaling 16ENSG0000014333351
RGS4 / P49798 / regulator of G protein signaling 4ENSG0000011715247
RGS3 / P49796 / regulator of G protein signaling 3ENSG0000013883543
RGS5 / O15539 / regulator of G protein signaling 5ENSG0000014324843
RGS2 / P41220 / regulator of G protein signaling 2ENSG0000011674141
RGS18 / Q9NS28 / regulator of G protein signaling 18ENSG0000015068139
RGS1 / Q08116 / regulator of G protein signaling 1ENSG0000009010436
RGS21 / Q2M5E4 / regulator of G protein signaling 21ENSG0000025314835
RGS19 / P49795 / regulator of G protein signaling 19ENSG0000017170033
RGS20 / O76081 / regulator of G protein signaling 20ENSG0000014750933
RGS13 / O14921 / regulator of G protein signaling 13ENSG0000012707432
RGS17 / Q9UGC6 / regulator of G protein signaling 17ENSG0000009184427


Protein motifs (from Interpro)
Interpro ID Name
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR034948  Regulator of G-protein signalling 8
 IPR034949  Regulator of G-protein signalling 8, RGS domain
 IPR036305  RGS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007213 G-protein coupled acetylcholine receptor signaling pathway ISS
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0060159 regulation of dopamine receptor signaling pathway ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0032809 neuronal cell body membrane ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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