ENSG00000138835


Homo sapiens

Features
Gene ID: ENSG00000138835
  
Biological name :RGS3
  
Synonyms : P49796 / regulator of G protein signaling 3 / RGS3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q32
Gene start: 113444731
Gene end: 113597743
  
Corresponding Affymetrix probe sets: 203823_at (Human Genome U133 Plus 2.0 Array)   220300_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417866
Ensembl peptide - ENSP00000378141
Ensembl peptide - ENSP00000417994
Ensembl peptide - ENSP00000482612
Ensembl peptide - ENSP00000479017
Ensembl peptide - ENSP00000436168
Ensembl peptide - ENSP00000420356
Ensembl peptide - ENSP00000418898
Ensembl peptide - ENSP00000259406
Ensembl peptide - ENSP00000312844
Ensembl peptide - ENSP00000340284
Ensembl peptide - ENSP00000343359
Ensembl peptide - ENSP00000363249
Ensembl peptide - ENSP00000363251
Ensembl peptide - ENSP00000363255
NCBI entrez gene - 5998     See in Manteia.
OMIM - 602189
RefSeq - XM_017015006
RefSeq - NM_001322214
RefSeq - NM_001322215
RefSeq - NM_017790
RefSeq - NM_130795
RefSeq - NM_134427
RefSeq - NM_144488
RefSeq - NM_144489
RefSeq - XM_006717219
RefSeq - XM_006717220
RefSeq - XM_006717222
RefSeq - XM_006717225
RefSeq - XM_006717226
RefSeq - XM_006717230
RefSeq - XM_011518893
RefSeq - XM_011518894
RefSeq - XM_011518896
RefSeq - XM_011518897
RefSeq - XM_011518898
RefSeq - XM_011518900
RefSeq - XM_011518901
RefSeq - XM_017015003
RefSeq - XM_017015004
RefSeq - XM_017015005
RefSeq - NM_001276260
RefSeq - NM_001276261
RefSeq - NM_001276262
RefSeq - NM_001282922
RefSeq - NM_001282923
RefSeq Peptide - NP_001269851
RefSeq Peptide - NP_001309144
RefSeq Peptide - NP_001338455
RefSeq Peptide - NP_060260
RefSeq Peptide - NP_570613
RefSeq Peptide - NP_602299
RefSeq Peptide - NP_652759
RefSeq Peptide - NP_652760
RefSeq Peptide - NP_001263189
RefSeq Peptide - NP_001263190
RefSeq Peptide - NP_001263191
RefSeq Peptide - NP_001269852
RefSeq Peptide - NP_001309143
swissprot - C9J582
swissprot - A0A087WUY2
swissprot - A0A024R841
swissprot - A0A024R833
swissprot - H7BXY1
swissprot - H7C539
swissprot - C9J6G2
swissprot - P49796
swissprot - Q5VXC0
swissprot - A0A024R831
Ensembl - ENSG00000138835
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgs3aENSDARG00000099746Danio rerio
 rgs3bENSDARG00000035132Danio rerio
 RGS3ENSGALG00000008881Gallus gallus
 Rgs3ENSMUSG00000059810Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGS20 / O76081 / regulator of G protein signaling 20ENSG000001475099
RGS4 / P49798 / regulator of G protein signaling 4ENSG000001171529
RGS5 / O15539 / regulator of G protein signaling 5ENSG000001432488
RGS16 / O15492 / regulator of G protein signaling 16ENSG000001433338
RGS2 / P41220 / regulator of G protein signaling 2ENSG000001167417
RGS1 / Q08116 / regulator of G protein signaling 1ENSG000000901047
RGS18 / Q9NS28 / regulator of G protein signaling 18ENSG000001506817
RGS8 / P57771 / regulator of G protein signaling 8ENSG000001358247
RGS19 / P49795 / regulator of G protein signaling 19ENSG000001717006
RGS17 / Q9UGC6 / regulator of G protein signaling 17ENSG000000918446
RGS21 / Q2M5E4 / regulator of G protein signaling 21ENSG000002531486
RGS13 / O14921 / regulator of G protein signaling 13ENSG000001270745


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001478  PDZ domain
 IPR011993  PH-like domain superfamily
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR034951  Regulator of G-protein signalling 3, RGS domain
 IPR035892  C2 domain superfamily
 IPR036034  PDZ superfamily
 IPR036305  RGS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity TAS
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway TAS
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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