ENSG00000127074


Homo sapiens

Features
Gene ID: ENSG00000127074
  
Biological name :RGS13
  
Synonyms : O14921 / regulator of G protein signaling 13 / RGS13
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q31.2
Gene start: 192636138
Gene end: 192660306
  
Corresponding Affymetrix probe sets: 1568751_at (Human Genome U133 Plus 2.0 Array)   1568752_s_at (Human Genome U133 Plus 2.0 Array)   210258_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000442837
Ensembl peptide - ENSP00000375853
NCBI entrez gene - 6003     See in Manteia.
OMIM - 607190
RefSeq - NM_002927
RefSeq - NM_144766
RefSeq Peptide - NP_002918
RefSeq Peptide - NP_658912
swissprot - O14921
swissprot - A0A024R989
Ensembl - ENSG00000127074
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgs13ENSDARG00000017653Danio rerio
 si:ch211-117l17.5ENSDARG00000100835Danio rerio
 RGS13ENSGALG00000026810Gallus gallus
 Rgs13ENSMUSG00000051079Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGS4 / P49798 / regulator of G protein signaling 4ENSG0000011715244
RGS1 / Q08116 / regulator of G protein signaling 1ENSG0000009010443
RGS2 / P41220 / regulator of G protein signaling 2ENSG0000011674142
RGS3 / P49796 / regulator of G protein signaling 3ENSG0000013883541
RGS20 / O76081 / regulator of G protein signaling 20ENSG0000014750940
RGS8 / P57771 / regulator of G protein signaling 8ENSG0000013582440
RGS19 / P49795 / regulator of G protein signaling 19ENSG0000017170039
RGS16 / O15492 / regulator of G protein signaling 16ENSG0000014333338
RGS5 / O15539 / regulator of G protein signaling 5ENSG0000014324838
RGS21 / Q2M5E4 / regulator of G protein signaling 21ENSG0000025314837
RGS18 / Q9NS28 / regulator of G protein signaling 18ENSG0000015068136
RGS17 / Q9UGC6 / regulator of G protein signaling 17ENSG0000009184435


Protein motifs (from Interpro)
Interpro ID Name
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR034954  Regulator of G-protein signalling 13
 IPR036305  RGS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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