ENSG00000090104


Homo sapiens

Features
Gene ID: ENSG00000090104
  
Biological name :RGS1
  
Synonyms : Q08116 / regulator of G protein signaling 1 / RGS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q31.2
Gene start: 192575727
Gene end: 192580031
  
Corresponding Affymetrix probe sets: 202988_s_at (Human Genome U133 Plus 2.0 Array)   202989_at (Human Genome U133 Plus 2.0 Array)   216834_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356429
Ensembl peptide - ENSP00000464323
NCBI entrez gene - 5996     See in Manteia.
OMIM - 600323
RefSeq - NM_002922
RefSeq Peptide - NP_002913
swissprot - A0A024R945
swissprot - Q08116
Ensembl - ENSG00000090104
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RGS1ENSGALG00000002549Gallus gallus
 Rgs1ENSMUSG00000026358Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGS4 / P49798 / regulator of G protein signaling 4ENSG0000011715238
RGS21 / Q2M5E4 / regulator of G protein signaling 21ENSG0000025314837
RGS3 / P49796 / regulator of G protein signaling 3ENSG0000013883537
RGS2 / P41220 / regulator of G protein signaling 2ENSG0000011674136
RGS18 / Q9NS28 / regulator of G protein signaling 18ENSG0000015068135
RGS5 / O15539 / regulator of G protein signaling 5ENSG0000014324835
RGS8 / P57771 / regulator of G protein signaling 8ENSG0000013582434
RGS16 / O15492 / regulator of G protein signaling 16ENSG0000014333334
RGS13 / O14921 / regulator of G protein signaling 13ENSG0000012707433
RGS19 / P49795 / regulator of G protein signaling 19ENSG0000017170031
RGS20 / O76081 / regulator of G protein signaling 20ENSG0000014750930
RGS17 / Q9UGC6 / regulator of G protein signaling 17ENSG0000009184427


Protein motifs (from Interpro)
Interpro ID Name
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR030409  Regulator of G-protein signalling 1
 IPR036305  RGS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway TAS
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IEA
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 biological_processGO:0061737 leukotriene signaling pathway IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IDA
 molecular_functionGO:0001965 G-protein alpha-subunit binding IPI
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005516 calmodulin binding TAS


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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