ENSG00000122484


Homo sapiens

Features
Gene ID: ENSG00000122484
  
Biological name :RPAP2
  
Synonyms : Q8IXW5 / RNA polymerase II associated protein 2 / RPAP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p22.1
Gene start: 92298965
Gene end: 92402056
  
Corresponding Affymetrix probe sets: 219504_s_at (Human Genome U133 Plus 2.0 Array)   222893_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476948
NCBI entrez gene - 79871     See in Manteia.
OMIM - 611476
RefSeq - XM_017002364
RefSeq - NM_024813
RefSeq - XM_017002362
RefSeq - XM_017002363
RefSeq - XM_005271223
RefSeq - XM_011542167
RefSeq Peptide - NP_079089
swissprot - Q8IXW5
Ensembl - ENSG00000122484
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpap2ENSDARG00000038397Danio rerio
 RPAP2ENSGALG00000005953Gallus gallus
 Rpap2ENSMUSG00000033773Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007308  Rtr1/RPAP2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009301 snRNA transcription IMP
 biological_processGO:0042795 snRNA transcription by RNA polymerase II TAS
 biological_processGO:0070940 dephosphorylation of RNA polymerase II C-terminal domain IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016591 DNA-directed RNA polymerase II, holoenzyme IDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity EXP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008420 CTD phosphatase activity IMP
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RNA polymerase II transcribes snRNA genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163125 RPRD2 / Q5VT52 / regulation of nuclear pre-mRNA domain containing 2  / complex / reaction
 ENSG00000141425 Q96P16 / RPRD1A / regulation of nuclear pre-mRNA domain containing 1A  / reaction / complex
 ENSG00000101413 Q9NQG5 / RPRD1B / regulation of nuclear pre-mRNA domain containing 1B  / reaction / complex






 

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