ENSG00000126785


Homo sapiens

Features
Gene ID: ENSG00000126785
  
Biological name :RHOJ
  
Synonyms : Q9H4E5 / ras homolog family member J / RHOJ
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q23.2
Gene start: 63204114
Gene end: 63293219
  
Corresponding Affymetrix probe sets: 1555233_at (Human Genome U133 Plus 2.0 Array)   1555234_a_at (Human Genome U133 Plus 2.0 Array)   235131_at (Human Genome U133 Plus 2.0 Array)   235489_at (Human Genome U133 Plus 2.0 Array)   238905_at (Human Genome U133 Plus 2.0 Array)   238906_s_at (Human Genome U133 Plus 2.0 Array)   243481_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451796
Ensembl peptide - ENSP00000316729
Ensembl peptide - ENSP00000451643
NCBI entrez gene - 57381     See in Manteia.
OMIM - 607653
RefSeq - XM_011536993
RefSeq - NM_020663
RefSeq - XM_006720214
RefSeq Peptide - NP_065714
swissprot - A0A024R692
swissprot - Q9H4E5
swissprot - G3V476
swissprot - G3V4H1
Ensembl - ENSG00000126785
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rhojENSDARG00000020250Danio rerio
 RHOJENSGALG00000011855Gallus gallus
 RhojENSMUSG00000046768Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RHOQ / P17081 / ras homolog family member QENSG0000011972973
CDC42 / P60953 / cell division cycle 42ENSG0000007083156
RAC1 / P63000 / Rac family small GTPase 1ENSG0000013623853
RAC3 / P60763 / Rac family small GTPase 3ENSG0000016975053
RAC2 / P15153 / Rac family small GTPase 2ENSG0000012834052
RHOU / Q7L0Q8 / ras homolog family member UENSG0000011657447
RHOG / P84095 / ras homolog family member GENSG0000017710547
RHOV / Q96L33 / ras homolog family member VENSG0000010414044
O94844 / RHOBTB1 / Rho related BTB domain containing 1ENSG0000007242233
Q9BYZ6 / RHOBTB2 / Rho related BTB domain containing 2ENSG0000000885332


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0007266 Rho protein signal transduction IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0030036 actin cytoskeleton organization IMP
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0061299 retina vasculature morphogenesis in camera-type eye IEA
 biological_processGO:0090050 positive regulation of cell migration involved in sprouting angiogenesis IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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