ENSG00000116574


Homo sapiens

Features
Gene ID: ENSG00000116574
  
Biological name :RHOU
  
Synonyms : Q7L0Q8 / ras homolog family member U / RHOU
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q42.13
Gene start: 228735077
Gene end: 228746669
  
Corresponding Affymetrix probe sets: 223168_at (Human Genome U133 Plus 2.0 Array)   223169_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355652
NCBI entrez gene - 58480     See in Manteia.
OMIM - 606366
RefSeq - NM_021205
RefSeq Peptide - NP_067028
swissprot - A0A024R3Q7
swissprot - Q7L0Q8
Ensembl - ENSG00000116574
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RHOU (1 of many)ENSDARG00000005626Danio rerio
 rhouaENSDARG00000019709Danio rerio
 ENSGALG00000025738Gallus gallus
 RhouENSMUSG00000039960Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RHOV / Q96L33 / ras homolog family member VENSG0000010414054
CDC42 / P60953 / cell division cycle 42ENSG0000007083143
RAC1 / P63000 / Rac family small GTPase 1ENSG0000013623842
RAC3 / P60763 / Rac family small GTPase 3ENSG0000016975041
RHOQ / P17081 / ras homolog family member QENSG0000011972940
RAC2 / P15153 / Rac family small GTPase 2ENSG0000012834040
RHOJ / Q9H4E5 / ras homolog family member JENSG0000012678539
RHOG / P84095 / ras homolog family member GENSG0000017710536
Q9BYZ6 / RHOBTB2 / Rho related BTB domain containing 2ENSG0000000885329
O94844 / RHOBTB1 / Rho related BTB domain containing 1ENSG0000007242229


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IEA
 biological_processGO:0007010 cytoskeleton organization IMP
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0016601 Rac protein signal transduction IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
Interleukin-4 and Interleukin-13 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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