ENSMUSG00000039960


Mus musculus

Features
Gene ID: ENSMUSG00000039960
  
Biological name :Rhou
  
Synonyms : Q9EQT3 / Rho-related GTP-binding protein RhoU / Rhou
  
Possible biological names infered from orthology : Q7L0Q8 / ras homolog family member U
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E1
Gene start: 123653929
Gene end: 123663884
  
Corresponding Affymetrix probe sets: 10576386 (MoGene1.0st)   1449027_at (Mouse Genome 430 2.0 Array)   1449028_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038915
NCBI entrez gene - 69581     See in Manteia.
MGI - MGI:1916831
RefSeq - NM_133955
RefSeq Peptide - NP_598716
swissprot - Q9EQT3
Ensembl - ENSMUSG00000039960
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RHOU (1 of many)ENSDARG00000005626Danio rerio
 rhouaENSDARG00000019709Danio rerio
 ENSGALG00000025738Gallus gallus
 RHOUENSG00000116574Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rhov / Q8VDU1 / Rho-related GTP-binding protein RhoV / Q96L33* / ras homolog family member V*ENSMUSG0000003422651
Rac1 / P63001 / RAS-related C3 botulinum substrate 1 / P63000* / Rac family small GTPase 1*ENSMUSG0000000184743
Cdc42 / P60766 / Cell division control ENSMUSG0000000669942
Rac3 / P60764 / RAS-related C3 botulinum substrate 3 / P60763* / Rac family small GTPase 3*ENSMUSG0000001801241
Rac2 / Q05144 / Ras-related C3 botulinum toxin substrate 2 / P15153* / Rac family small GTPase 2*ENSMUSG0000003322039
Rhoq / Q8R527 / Rho-related GTP-binding protein RhoQ / P17081* / ras homolog family member Q*ENSMUSG0000002414339
Rhoj / Q9ER71 / ras homolog family member J / Q9H4E5*ENSMUSG0000004676838
Rhog / P84096 / ras homolog family member G / P84095*ENSMUSG0000007398236
Q91V93 / Rhobtb2 / Rho-related BTB domain-containing protein 2 / Q9BYZ6* / Rho related BTB domain containing 2*ENSMUSG0000002207528
Q9DAK3 / Rhobtb1 / Rho-related BTB domain-containing protein 1 / O94844* / Rho related BTB domain containing 1*ENSMUSG0000001994428


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IDA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0016601 Rac protein signal transduction IDA
 biological_processGO:0030036 actin cytoskeleton organization IDA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IMP
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Rhobtb3tm1a(KOMP)Wtsi/Rhobtb3tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Rhobtb3tm1a(KOMP)Wtsi/Wtsi

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Rhobtb3tm1a(KOMP)Wtsi/Rhobtb3tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Rhobtb3tm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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