Manteia

ENSDARG00000019709

Danio rerio

Features

Gene ID:	ENSDARG00000019709

Biological name :	rhoua

Synonyms :	ras homolog family member Ua / rhoua

Possible biological names infered from orthology :	Q7L0Q8 / Q9EQT3 / ras homolog family member U / Rho-related GTP-binding protein RhoU / RHOU

Species:	Danio rerio

Chr. number:	13
Strand:	-1
Band:
Gene start:	24371815
Gene end:	24379271

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000046359 NCBI entrez gene - 492802 See in Manteia. RefSeq - NM_001007443 RefSeq Peptide - NP_001007444 swissprot - Q5U3T8 ZFIN ID - ZDB-GENE-040618-3 Ensembl - ENSDARG00000019709

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
	ENSGALG00000025738	Gallus gallus
RHOU	ENSG00000116574	Homo sapiens
Rhou	ENSMUSG00000039960	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
RHOU (1 of many) / si:ch211-133l11.10 / RHOU* / Q9EQT3* / Q7L0Q8* / ras homolog family member U* / Rho-related GTP-binding protein RhoU *	ENSDARG00000005626	60
rhoub / ras homolog family member Ub	ENSDARG00000012968	60
rhov / ras homolog family member V / Q8VDU1* / Q96L33* / Rho-related GTP-binding protein RhoV *	ENSDARG00000070434	48
cdc42 / cell division cycle 42 / P60766* / P60953* / Cell division control *	ENSDARG00000044573	44
cdc42l / cell division cycle 42, like	ENSDARG00000040158	43
rac1a / Rac family small GTPase 1a / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000074849	42
rac3b / Rac family small GTPase 3b / RAC3* / P60764* / P60763* / Rac family small GTPase 3* / RAS-related C3 botulinum substrate 3*	ENSDARG00000020795	41
rhoq / ras homolog family member Q / P17081* / Q8R527* / Rho-related GTP-binding protein RhoQ *	ENSDARG00000025953	41
rac1b / Rac family small GTPase 1b / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000087954	41
rac3a / Rac family small GTPase 3a / RAC3* / P60763* / Rac family small GTPase 3*	ENSDARG00000090062	41
rhoj / ras homolog family member J / Q9ER71* / Q9H4E5*	ENSDARG00000020250	40
rac2 / Rac family small GTPase 2 / P15153* / Q05144* / Ras-related C3 botulinum toxin substrate 2 *	ENSDARG00000038010	40
cdc42l2 / cell division cycle 42 like 2	ENSDARG00000057869	39
rhoga / ras homolog family member Ga / RHOG* / P84095* / P84096* / ras homolog family member G*	ENSDARG00000068653	37
rhogc / ras homolog gene family, member Gc	ENSDARG00000028401	37
rac1l / Rac family small GTPase 1, like / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000054649	37
si:ch211-1f22.1 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000013203	37
rhogb / ras homolog family member Gb / RHOG* / P84095* / P84096* / ras homolog family member G*	ENSDARG00000004301	36
rhogd / ras homolog gene family, member Gd	ENSDARG00000030608	36
si:ch211-1f22.2 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000096666	35

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR003578	Small GTPase superfamily, Rho type
IPR005225	Small GTP-binding protein domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007264	small GTPase mediated signal transduction	IEA
biological_process	GO:0030155	regulation of cell adhesion	IMP
biological_process	GO:0036302	atrioventricular canal development	IMP
cellular_component	GO:0005622	intracellular	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005525	GTP binding	IEA

Pathways (from Reactome)

Pathway description

Rho GTPase cycle

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000114	heart	heart edematous , abnormal	Show
ZFA:0001315	atrioventricular canal	atrioventricular canal malformed , abnormal atrioventricular canal cardiac muscle cell morphology , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr