ENSDARG00000004301


Danio rerio

Features
Gene ID: ENSDARG00000004301
  
Biological name :rhogb
  
Synonyms : ras homolog family member Gb / rhogb
  
Possible biological names infered from orthology : P84095 / P84096 / ras homolog family member G / RHOG
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 30937690
Gene end: 30951909
  
Corresponding Affymetrix probe sets: Dr.9665.1.S1_at (Zebrafish Array)   NM_200040_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000027635
Ensembl peptide - ENSDARP00000156556
NCBI entrez gene - 336933     See in Manteia.
RefSeq - NM_200040
RefSeq Peptide - NP_956334
swissprot - Q803F2
ZFIN ID - ZDB-GENE-030131-8877
Ensembl - ENSDARG00000004301
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RHOGENSGALG00000026995Gallus gallus
 RHOGENSG00000177105Homo sapiens
 RhogENSMUSG00000073982Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rhogd / ras homolog gene family, member GdENSDARG0000003060876
rhoga / ras homolog family member Ga / RHOG* / P84095* / P84096* / ras homolog family member G*ENSDARG0000006865375
rhogc / ras homolog gene family, member GcENSDARG0000002840173
rac1b / Rac family small GTPase 1b / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000008795468
rac2 / Rac family small GTPase 2 / P15153* / Q05144* / Ras-related C3 botulinum toxin substrate 2 *ENSDARG0000003801068
rac1a / Rac family small GTPase 1a / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000007484968
rac3a / Rac family small GTPase 3a / RAC3* / P60763* / Rac family small GTPase 3*ENSDARG0000009006266
rac3b / Rac family small GTPase 3b / RAC3* / P60764* / P60763* / Rac family small GTPase 3* / RAS-related C3 botulinum substrate 3*ENSDARG0000002079566
cdc42 / cell division cycle 42 / P60766* / P60953* / Cell division control *ENSDARG0000004457361
cdc42l / cell division cycle 42, likeENSDARG0000004015860
si:ch211-1f22.1 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000001320355
rac1l / Rac family small GTPase 1, like / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000005464953
rhoq / ras homolog family member Q / P17081* / Q8R527* / Rho-related GTP-binding protein RhoQ *ENSDARG0000002595352
rhoj / ras homolog family member J / Q9ER71* / Q9H4E5*ENSDARG0000002025052
si:ch211-1f22.2 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000009666651
rac1l / si:ch73-94k4.2 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000009654949
rhoua / ras homolog family member Ua / RHOU* / Q9EQT3* / Q7L0Q8* / ras homolog family member U* / Rho-related GTP-binding protein RhoU *ENSDARG0000001970948
cdc42l2 / cell division cycle 42 like 2ENSDARG0000005786948
RHOU (1 of many) / si:ch211-133l11.10 / RHOU* / Q9EQT3* / Q7L0Q8* / ras homolog family member U* / Rho-related GTP-binding protein RhoU *ENSDARG0000000562646
rhoub / ras homolog family member UbENSDARG0000001296846


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0009617 response to bacterium IDA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
GPVI-mediated activation cascade
Rho GTPase cycle
G alpha (12/13) signalling events
RHO GTPases activate KTN1
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009796 klc1a / kinesin light chain 1a / KLC1* / Q07866* / AL139300.1* / kinesin light chain 1* / kinesin light chain 1 isoform 1G *  / reaction / complex
 ENSDARG00000032802 ktn1 / kinectin 1 / Q86UP2*  / reaction / complex
 ENSDARG00000038524 pik3r1 / phosphoinositide-3-kinase, regulatory subunit 1 (alpha) / P26450* / P27986* / phosphoinositide-3-kinase regulatory subunit 1*  / complex / reaction
 ENSDARG00000075456 pik3ca / phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha / P42336* / P42337* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform *  / reaction / complex
 ENSDARG00000075962 vav3b / vav 3 guanine nucleotide exchange factor b / VAV3* / Q9UKW4* / Q9R0C8* / vav 3 oncogene* / vav guanine nucleotide exchange factor 3*  / reaction
 ENSDARG00000073765 gna13a / guanine nucleotide binding protein (G protein), alpha 13a / GNA13* / Q14344* / P27601* / G protein subunit alpha 13* / guanine nucleotide binding protein, alpha 13*  / reaction
 ENSDARG00000055837 arhgef1b / Rho guanine nucleotide exchange factor (GEF) 1b / Q61210* / Q92888* / ARHGEF1* / Rho guanine nucleotide exchange factor 1*  / reaction
 ENSDARG00000044718 vav2 / vav 2 guanine nucleotide exchange factor / Q60992* / P52735* / vav 2 oncogene* / vav guanine nucleotide exchange factor 2*  / reaction
 ENSDARG00000098936 kif5aa / kinesin family member 5A, a / KIF5A* / Q12840* / kinesin family member 5A*  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr