Manteia

ENSDARG00000068653

Danio rerio

Features

Gene ID:	ENSDARG00000068653

Biological name :	rhoga

Synonyms :	ras homolog family member Ga / rhoga

Possible biological names infered from orthology :	P84095 / P84096 / ras homolog family member G / RHOG

Species:	Danio rerio

Chr. number:	15
Strand:	-1
Band:
Gene start:	38201964
Gene end:	38218320

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000126762 Ensembl peptide - ENSDARP00000148859 NCBI entrez gene - 556424 See in Manteia. RefSeq - NM_001082804 RefSeq Peptide - NP_001076273 swissprot - Q1LY89 ZFIN ID - ZDB-GENE-060503-820 Ensembl - ENSDARG00000068653

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
RHOG	ENSGALG00000026995	Gallus gallus
RHOG	ENSG00000177105	Homo sapiens
Rhog	ENSMUSG00000073982	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
rhogb / ras homolog family member Gb / RHOG* / P84095* / P84096* / ras homolog family member G*	ENSDARG00000004301	75
rhogd / ras homolog gene family, member Gd	ENSDARG00000030608	73
rhogc / ras homolog gene family, member Gc	ENSDARG00000028401	72
rac1a / Rac family small GTPase 1a / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000074849	67
rac1b / Rac family small GTPase 1b / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000087954	66
rac3b / Rac family small GTPase 3b / RAC3* / P60764* / P60763* / Rac family small GTPase 3* / RAS-related C3 botulinum substrate 3*	ENSDARG00000020795	66
rac2 / Rac family small GTPase 2 / P15153* / Q05144* / Ras-related C3 botulinum toxin substrate 2 *	ENSDARG00000038010	66
rac3a / Rac family small GTPase 3a / RAC3* / P60763* / Rac family small GTPase 3*	ENSDARG00000090062	65
cdc42 / cell division cycle 42 / P60766* / P60953* / Cell division control *	ENSDARG00000044573	61
cdc42l / cell division cycle 42, like	ENSDARG00000040158	61
si:ch211-1f22.1 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000013203	55
rhoq / ras homolog family member Q / P17081* / Q8R527* / Rho-related GTP-binding protein RhoQ *	ENSDARG00000025953	53
rac1l / Rac family small GTPase 1, like / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000054649	52
rhoj / ras homolog family member J / Q9ER71* / Q9H4E5*	ENSDARG00000020250	51
si:ch211-1f22.2 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000096666	50
rhoua / ras homolog family member Ua / RHOU* / Q9EQT3* / Q7L0Q8* / ras homolog family member U* / Rho-related GTP-binding protein RhoU *	ENSDARG00000019709	50
cdc42l2 / cell division cycle 42 like 2	ENSDARG00000057869	49
RHOU (1 of many) / si:ch211-133l11.10 / RHOU* / Q9EQT3* / Q7L0Q8* / ras homolog family member U* / Rho-related GTP-binding protein RhoU *	ENSDARG00000005626	47
rhoub / ras homolog family member Ub	ENSDARG00000012968	46
rac1l / si:ch73-94k4.2 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*	ENSDARG00000096549	46

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR003578	Small GTPase superfamily, Rho type
IPR005225	Small GTP-binding protein domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007264	small GTPase mediated signal transduction	IEA
cellular_component	GO:0005622	intracellular	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005525	GTP binding	IEA

Pathways (from Reactome)

Pathway description

GPVI-mediated activation cascade

Rho GTPase cycle

G alpha (12/13) signalling events

RHO GTPases activate KTN1

Neutrophil degranulation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000009796	klc1a / kinesin light chain 1a / KLC1* / Q07866* / AL139300.1* / kinesin light chain 1* / kinesin light chain 1 isoform 1G *	/ reaction / complex
ENSDARG00000032802	ktn1 / kinectin 1 / Q86UP2*	/ reaction / complex
ENSDARG00000038524	pik3r1 / phosphoinositide-3-kinase, regulatory subunit 1 (alpha) / P26450* / P27986* / phosphoinositide-3-kinase regulatory subunit 1*	/ reaction / complex
ENSDARG00000075456	pik3ca / phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha / P42336* / P42337* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform *	/ reaction / complex
ENSDARG00000075962	vav3b / vav 3 guanine nucleotide exchange factor b / VAV3* / Q9UKW4* / Q9R0C8* / vav 3 oncogene* / vav guanine nucleotide exchange factor 3*	/ reaction
ENSDARG00000073765	gna13a / guanine nucleotide binding protein (G protein), alpha 13a / GNA13* / Q14344* / P27601* / G protein subunit alpha 13* / guanine nucleotide binding protein, alpha 13*	/ reaction
ENSDARG00000055837	arhgef1b / Rho guanine nucleotide exchange factor (GEF) 1b / Q61210* / Q92888* / ARHGEF1* / Rho guanine nucleotide exchange factor 1*	/ reaction
ENSDARG00000044718	vav2 / vav 2 guanine nucleotide exchange factor / Q60992* / P52735* / vav 2 oncogene* / vav guanine nucleotide exchange factor 2*	/ reaction
ENSDARG00000098936	kif5aa / kinesin family member 5A, a / KIF5A* / Q12840* / kinesin family member 5A*	/ reaction / complex

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr