ENSDARG00000087954


Danio rerio

Features
Gene ID: ENSDARG00000087954
  
Biological name :rac1b
  
Synonyms : rac1b / Rac family small GTPase 1b
  
Possible biological names infered from orthology : P63000 / P63001 / RAC1 / Rac family small GTPase 1 / RAS-related C3 botulinum substrate 1
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 56574623
Gene end: 56594285
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000106208
NCBI entrez gene - 562838     See in Manteia.
RefSeq - NM_001039818
RefSeq Peptide - NP_001034907
swissprot - Q29RC5
ZFIN ID - ZDB-GENE-060312-45
Ensembl - ENSDARG00000087954
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAC1ENSGALG00000007130Gallus gallus
 RAC1ENSG00000136238Homo sapiens
 Rac1ENSMUSG00000001847Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rac1a / Rac family small GTPase 1a / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000007484997
rac3a / Rac family small GTPase 3a / RAC3* / P60763* / Rac family small GTPase 3*ENSDARG0000009006294
rac3b / Rac family small GTPase 3b / RAC3* / P60764* / P60763* / Rac family small GTPase 3* / RAS-related C3 botulinum substrate 3*ENSDARG0000002079594
rac2 / Rac family small GTPase 2 / P15153* / Q05144* / Ras-related C3 botulinum toxin substrate 2 *ENSDARG0000003801092
cdc42 / cell division cycle 42 / P60766* / P60953* / Cell division control *ENSDARG0000004457371
rhogc / ras homolog gene family, member GcENSDARG0000002840170
si:ch211-1f22.1 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000001320370
rhogd / ras homolog gene family, member GdENSDARG0000003060869
cdc42l / cell division cycle 42, likeENSDARG0000004015869
rac1l / Rac family small GTPase 1, like / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000005464968
rhogb / ras homolog family member Gb / RHOG* / P84095* / P84096* / ras homolog family member G*ENSDARG0000000430167
rhoga / ras homolog family member Ga / RHOG* / P84095* / P84096* / ras homolog family member G*ENSDARG0000006865366
rhoq / ras homolog family member Q / P17081* / Q8R527* / Rho-related GTP-binding protein RhoQ *ENSDARG0000002595364
si:ch211-1f22.2 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000009666664
rhoj / ras homolog family member J / Q9ER71* / Q9H4E5*ENSDARG0000002025063
rac1l / si:ch73-94k4.2 / RAC1* / P63001* / P63000* / Rac family small GTPase 1* / RAS-related C3 botulinum substrate 1*ENSDARG0000009654960
rhoua / ras homolog family member Ua / RHOU* / Q9EQT3* / Q7L0Q8* / ras homolog family member U* / Rho-related GTP-binding protein RhoU *ENSDARG0000001970955
cdc42l2 / cell division cycle 42 like 2ENSDARG0000005786955
rhoub / ras homolog family member UbENSDARG0000001296851
RHOU (1 of many) / si:ch211-133l11.10 / RHOU* / Q9EQT3* / Q7L0Q8* / ras homolog family member U* / Rho-related GTP-binding protein RhoU *ENSDARG0000000562651


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
GPVI-mediated activation cascade
NRAGE signals death through JNK
Rho GTPase cycle
Regulation of actin dynamics for phagocytic cup formation
DAP12 signaling
FCERI mediated MAPK activation
CD28 dependent Vav1 pathway
EPHB-mediated forward signaling
Ephrin signaling
EPH-ephrin mediated repulsion of cells
Sema3A PAK dependent Axon repulsion
PCP/CE pathway
G alpha (12/13) signalling events
Sema4D mediated inhibition of cell attachment and migration
DCC mediated attractive signaling
VEGFA-VEGFR2 Pathway
Signal transduction by L1
VEGFR2 mediated vascular permeability
RHO GTPases activate PKNs
RHO GTPases activate CIT
RHO GTPases activate KTN1
RHO GTPases activate IQGAPs
RHO GTPases activate PAKs
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate Formins
RHO GTPases Activate NADPH Oxidases
MAPK6/MAPK4 signaling
Neutrophil degranulation
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
MET activates RAP1 and RAC1
NTRK2 activates RAC1
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart bilateral symmetry , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
pronephros cilium assembly decreased process quality , abnormal
Show

 ZFA:0001558 pronephric tubule pronephric tubule ciliary basal body organization decreased process quality , abnormal
pronephric tubule ciliary basal body separated from pronephric tubule apical plasma membrane, abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr