ENSMUSG00000024143


Mus musculus

Features
Gene ID: ENSMUSG00000024143
  
Biological name :Rhoq
  
Synonyms : Q8R527 / Rhoq / Rho-related GTP-binding protein RhoQ
  
Possible biological names infered from orthology : P17081 / ras homolog family member Q
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: E4
Gene start: 86963082
Gene end: 87000069
  
Corresponding Affymetrix probe sets: 10447341 (MoGene1.0st)   1427918_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116780
Ensembl peptide - ENSMUSP00000024956
NCBI entrez gene - 104215     See in Manteia.
MGI - MGI:1931553
RefSeq - NM_145491
RefSeq Peptide - NP_663466
swissprot - D3Z3L1
swissprot - Q8R527
Ensembl - ENSMUSG00000024143
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rhoqENSDARG00000025953Danio rerio
 RHOQENSGALG00000010010Gallus gallus
 RHOQENSG00000119729Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rhoj / Q9ER71 / ras homolog family member J / Q9H4E5*ENSMUSG0000004676876
Cdc42 / P60766 / Cell division control ENSMUSG0000000669962
Rac1 / P63001 / RAS-related C3 botulinum substrate 1 / P63000* / Rac family small GTPase 1*ENSMUSG0000000184760
Rac3 / P60764 / RAS-related C3 botulinum substrate 3 / P60763* / Rac family small GTPase 3*ENSMUSG0000001801258
Rac2 / Q05144 / Ras-related C3 botulinum toxin substrate 2 / P15153* / Rac family small GTPase 2*ENSMUSG0000003322056
Rhog / P84096 / ras homolog family member G / P84095*ENSMUSG0000007398251
Rhou / Q9EQT3 / Rho-related GTP-binding protein RhoU / Q7L0Q8* / ras homolog family member U*ENSMUSG0000003996050
Rhov / Q8VDU1 / Rho-related GTP-binding protein RhoV / Q96L33* / ras homolog family member V*ENSMUSG0000003422649
Q9DAK3 / Rhobtb1 / Rho-related BTB domain-containing protein 1 / O94844* / Rho related BTB domain containing 1*ENSMUSG0000001994436
Q91V93 / Rhobtb2 / Rho-related BTB domain-containing protein 2 / Q9BYZ6* / Rho related BTB domain containing 2*ENSMUSG0000002207535


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0030036 actin cytoskeleton organization TAS
 biological_processGO:0030866 cortical actin cytoskeleton organization IMP
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046039 GTP metabolic process IEA
 biological_processGO:0046325 negative regulation of glucose import IC
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0051491 positive regulation of filopodium assembly IEA
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005884 actin filament IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0045121 membrane raft IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005522 profilin binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0032427 GBD domain binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr