ENSG00000132005


Homo sapiens

Features
Gene ID: ENSG00000132005
  
Biological name :RFX1
  
Synonyms : P22670 / regulatory factor X1 / RFX1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.12
Gene start: 13961538
Gene end: 14007039
  
Corresponding Affymetrix probe sets: 206321_at (Human Genome U133 Plus 2.0 Array)   226786_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000254325
Ensembl peptide - ENSP00000464960
NCBI entrez gene - 5989     See in Manteia.
OMIM - 600006
RefSeq - XM_011528170
RefSeq - NM_002918
RefSeq - XM_011528167
RefSeq - XM_011528168
RefSeq - XM_011528169
RefSeq - XM_011528165
RefSeq - XM_011528166
RefSeq Peptide - NP_002909
swissprot - P22670
swissprot - K7EIZ8
Ensembl - ENSG00000132005
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rfx1aENSDARG00000005883Danio rerio
 rfx1bENSDARG00000075904Danio rerio
 Rfx1ENSMUSG00000031706Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RFX3 / P48380 / regulatory factor X3ENSG0000008029845
RFX2 / P48378 / regulatory factor X2ENSG0000008790342
RFX4 / Q33E94 / regulatory factor X4ENSG0000011178320
RFX6 / Q8HWS3 / regulatory factor X6ENSG0000018500220
RFX7 / Q2KHR2 / regulatory factor X7ENSG0000018182712
RFX5 / P48382 / regulatory factor X5ENSG000001433909
RFX8 / Q6ZV50 / RFX family member 8, lacking RFX DNA binding domainENSG000001964609


Protein motifs (from Interpro)
Interpro ID Name
 IPR003150  DNA-binding RFX-type winged-helix domain
 IPR007668  RFX1 transcription activation region
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006955 immune response TAS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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