ENSG00000087903


Homo sapiens

Features
Gene ID: ENSG00000087903
  
Biological name :RFX2
  
Synonyms : P48378 / regulatory factor X2 / RFX2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 5993164
Gene end: 6199572
  
Corresponding Affymetrix probe sets: 208031_s_at (Human Genome U133 Plus 2.0 Array)   226872_at (Human Genome U133 Plus 2.0 Array)   242966_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468561
Ensembl peptide - ENSP00000467979
Ensembl peptide - ENSP00000468036
Ensembl peptide - ENSP00000306335
Ensembl peptide - ENSP00000352076
Ensembl peptide - ENSP00000464826
Ensembl peptide - ENSP00000465122
Ensembl peptide - ENSP00000465135
Ensembl peptide - ENSP00000466028
Ensembl peptide - ENSP00000466177
Ensembl peptide - ENSP00000466890
Ensembl peptide - ENSP00000467166
Ensembl peptide - ENSP00000467736
NCBI entrez gene - 5990     See in Manteia.
OMIM - 142765
RefSeq - XM_017027108
RefSeq - NM_000635
RefSeq - NM_134433
RefSeq - XM_011528171
RefSeq - XM_011528172
RefSeq - XM_017027107
RefSeq Peptide - NP_602309
RefSeq Peptide - NP_000626
swissprot - K7EQY9
swissprot - K7ES56
swissprot - P48378
swissprot - K7EIN5
swissprot - K7EJD4
swissprot - K7EJE4
swissprot - K7ELD5
swissprot - K7ELQ7
swissprot - K7EQA0
swissprot - K7ENC9
swissprot - K7EQU2
Ensembl - ENSG00000087903
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rfx2ENSDARG00000013575Danio rerio
 RFX2ENSGALG00000001773Gallus gallus
 Rfx2ENSMUSG00000024206Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RFX3 / P48380 / regulatory factor X3ENSG0000008029866
RFX1 / P22670 / regulatory factor X1ENSG0000013200557
RFX4 / Q33E94 / regulatory factor X4ENSG0000011178325
RFX6 / Q8HWS3 / regulatory factor X6ENSG0000018500225
RFX7 / Q2KHR2 / regulatory factor X7ENSG0000018182714
RFX8 / Q6ZV50 / RFX family member 8, lacking RFX DNA binding domainENSG0000019646013
RFX5 / P48382 / regulatory factor X5ENSG0000014339010


Protein motifs (from Interpro)
Interpro ID Name
 IPR003150  DNA-binding RFX-type winged-helix domain
 IPR007668  RFX1 transcription activation region
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001675 acrosome assembly ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007286 spermatid development ISS
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060271 cilium assembly ISS
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISS
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr