ENSG00000134072


Homo sapiens

Features
Gene ID: ENSG00000134072
  
Biological name :CAMK1
  
Synonyms : calcium/calmodulin dependent protein kinase I / CAMK1 / Q14012
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p25.3
Gene start: 9757342
Gene end: 9769992
  
Corresponding Affymetrix probe sets: 204392_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393238
Ensembl peptide - ENSP00000404587
Ensembl peptide - ENSP00000256460
Ensembl peptide - ENSP00000380447
NCBI entrez gene - 8536     See in Manteia.
OMIM - 604998
RefSeq - XM_017007354
RefSeq - NM_003656
RefSeq - XM_005265516
RefSeq - XM_005265517
RefSeq Peptide - NP_003647
swissprot - B0YIY3
swissprot - Q14012
swissprot - C9JES6
swissprot - F8W6S9
swissprot - H7C071
Ensembl - ENSG00000134072
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 camk1aENSDARG00000060116Danio rerio
 camk1bENSDARG00000029474Danio rerio
 CAMK1ENSGALG00000029912Gallus gallus
 Camk1ENSMUSG00000030272Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAMK1D / Q8IU85 / calcium/calmodulin dependent protein kinase IDENSG0000018304974
CAMK1G / Q96NX5 / calcium/calmodulin dependent protein kinase IGENSG0000000811863
PNCK / Q6P2M8 / pregnancy up-regulated nonubiquitous CaM kinaseENSG0000013082261
CAMKV / Q8NCB2 / CaM kinase like vesicle associatedENSG0000016407642
CAMK4 / Q16566 / calcium/calmodulin dependent protein kinase IVENSG0000015249542
PSKH1 / P11801 / protein serine kinase H1ENSG0000015979238
CAMK2G / Q13555 / calcium/calmodulin dependent protein kinase II gammaENSG0000014866037
CAMK2D / Q13557 / calcium/calmodulin dependent protein kinase II deltaENSG0000014534936
CAMK2B / Q13554 / calcium/calmodulin dependent protein kinase II betaENSG0000005840436
CAMK2A / Q9UQM7 / calcium/calmodulin dependent protein kinase II alphaENSG0000007080836
PSKH2 / Q96QS6 / protein serine kinase H2ENSG0000014761336


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006913 nucleocytoplasmic transport IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0010976 positive regulation of neuron projection development IDA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IBA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0032880 regulation of protein localization IDA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IMP
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043393 regulation of protein binding IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0046827 positive regulation of protein export from nucleus IDA
 biological_processGO:0051147 regulation of muscle cell differentiation IDA
 biological_processGO:0051149 positive regulation of muscle cell differentiation IMP
 biological_processGO:0051835 positive regulation of synapse structural plasticity IMP
 biological_processGO:0060143 positive regulation of syncytium formation by plasma membrane fusion IMP
 biological_processGO:0060999 positive regulation of dendritic spine development IMP
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IDA
 biological_processGO:1901985 positive regulation of protein acetylation IMP
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004683 calmodulin-dependent protein kinase activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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