ENSMUSG00000030272


Mus musculus

Features
Gene ID: ENSMUSG00000030272
  
Biological name :Camk1
  
Synonyms : calcium/calmodulin-dependent protein kinase I / Camk1 / Q91YS8
  
Possible biological names infered from orthology : Q14012
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: E3
Gene start: 113334124
Gene end: 113343984
  
Corresponding Affymetrix probe sets: 10546891 (MoGene1.0st)   1417604_at (Mouse Genome 430 2.0 Array)   1417605_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117749
Ensembl peptide - ENSMUSP00000032409
NCBI entrez gene - 52163     See in Manteia.
MGI - MGI:1098535
RefSeq - NM_133926
RefSeq Peptide - NP_598687
swissprot - D3Z368
swissprot - Q3UY68
swissprot - Q91YS8
Ensembl - ENSMUSG00000030272
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 camk1aENSDARG00000060116Danio rerio
 camk1bENSDARG00000029474Danio rerio
 CAMK1ENSGALG00000029912Gallus gallus
 CAMK1ENSG00000134072Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Camk1d / Q8BW96 / calcium/calmodulin-dependent protein kinase ID / Q8IU85*ENSMUSG0000003914574
Camk1g / Q91VB2 / Calcium/calmodulin-dependent protein kinase type 1G / Q96NX5* / calcium/calmodulin dependent protein kinase IG*ENSMUSG0000001617963
Pnck / Q9QYK9 / pregnancy upregulated non-ubiquitously expressed CaM kinase / Q6P2M8* / pregnancy up-regulated nonubiquitous CaM kinase*ENSMUSG0000000201260
Camkv / Q3UHL1 / CaM kinase-like vesicle-associated protein / Q8NCB2* / CaM kinase like vesicle associated*ENSMUSG0000003293642
Camk4 / calcium/calmodulin-dependent protein kinase IV / Q16566*ENSMUSG0000003812841
Pskh1 / Q91YA2 / protein serine kinase H1 / P11801*ENSMUSG0000004831038
Camk2g / Q923T9 / Calcium/calmodulin-dependent protein kinase type II subunit gamma / Q13555* / calcium/calmodulin dependent protein kinase II gamma*ENSMUSG0000002182037
Camk2b / P28652 / Calcium/calmodulin-dependent protein kinase type II subunit beta / Q13554* / calcium/calmodulin dependent protein kinase II beta*ENSMUSG0000005789736
Camk2a / P11798 / Calcium/calmodulin-dependent protein kinase type II subunit alpha / Q9UQM7* / calcium/calmodulin dependent protein kinase II alpha*ENSMUSG0000002461736
Camk2d / Q6PHZ2 / Mus musculus calcium/calmodulin-dependent protein kinase II, delta (Camk2d), transcript variant 8, mRNA. / Q13557* / calcium/calmodulin dependent protein kinase II delta*ENSMUSG0000005381936


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006913 nucleocytoplasmic transport IGI
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0010976 positive regulation of neuron projection development IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IBA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0032880 regulation of protein localization IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043393 regulation of protein binding ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046827 positive regulation of protein export from nucleus IEA
 biological_processGO:0051147 regulation of muscle cell differentiation ISO
 biological_processGO:0051149 positive regulation of muscle cell differentiation IEA
 biological_processGO:0051835 positive regulation of synapse structural plasticity IEA
 biological_processGO:0060143 positive regulation of syncytium formation by plasma membrane fusion IEA
 biological_processGO:0060999 positive regulation of dendritic spine development IEA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IEA
 biological_processGO:1901985 positive regulation of protein acetylation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004683 calmodulin-dependent protein kinase activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002965 hyperalbuminemia "blood albumin concentration above the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Pofut2tm2.2Bch/Pofut2tm2.2Bch
Genetic Background: B6.Cg-Pofut2tm2.2Bch

 MP:0003019 increased circulating chloride level "elevated concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Pofut2tm2.2Bch/Pofut2tm2.2Bch
Genetic Background: B6.Cg-Pofut2tm2.2Bch

 MP:0003049 abnormal lumbar vertebrae morphology "malformation of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pofut2tm2.2Bch/Pofut2tm2.2Bch
Genetic Background: B6.Cg-Pofut2tm2.2Bch

 MP:0013278 decreased fasted circulating glucose level "reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
Show

Allelic Composition: Pofut2tm2.2Bch/Pofut2tm2.2Bch
Genetic Background: B6.Cg-Pofut2tm2.2Bch

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr