ENSG00000135373


Homo sapiens

Features
Gene ID: ENSG00000135373
  
Biological name :EHF
  
Synonyms : EHF / ETS homologous factor / Q9NZC4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p13
Gene start: 34621093
Gene end: 34661057
  
Corresponding Affymetrix probe sets: 219850_s_at (Human Genome U133 Plus 2.0 Array)   222932_at (Human Genome U133 Plus 2.0 Array)   224189_x_at (Human Genome U133 Plus 2.0 Array)   225645_at (Human Genome U133 Plus 2.0 Array)   232360_at (Human Genome U133 Plus 2.0 Array)   232361_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433508
Ensembl peptide - ENSP00000436357
Ensembl peptide - ENSP00000436158
Ensembl peptide - ENSP00000435837
Ensembl peptide - ENSP00000435835
Ensembl peptide - ENSP00000434395
Ensembl peptide - ENSP00000257831
Ensembl peptide - ENSP00000399733
Ensembl peptide - ENSP00000432460
Ensembl peptide - ENSP00000432905
NCBI entrez gene - 26298     See in Manteia.
OMIM - 605439
RefSeq - XM_005252860
RefSeq - XM_005252861
RefSeq - XM_011519984
RefSeq - NM_001206615
RefSeq - NM_001206616
RefSeq - NM_012153
RefSeq - XM_017017534
RefSeq - XM_011519985
RefSeq - XM_011519983
RefSeq - XM_005252857
RefSeq - XM_005252862
RefSeq Peptide - NP_036285
RefSeq Peptide - NP_001193544
RefSeq Peptide - NP_001193545
swissprot - Q9NZC4
swissprot - E9PQX0
swissprot - E9PN75
swissprot - E9PPS9
swissprot - E9PQR6
Ensembl - ENSG00000135373
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ehfENSDARG00000052115Danio rerio
 EHFENSGALG00000007817Gallus gallus
 EhfENSMUSG00000012350Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELF3 / P78545 / E74 like ETS transcription factor 3ENSG0000016343537
ELF5 / Q9UKW6 / E74 like ETS transcription factor 5ENSG0000013537435
ELF2 / Q15723 / E74 like ETS transcription factor 2ENSG0000010938120
ETV6 / P41212 / ETS variant 6ENSG0000013908319
ELF1 / P32519 / E74 like ETS transcription factor 1ENSG0000012069018
ETV7 / Q9Y603 / ETS variant 7ENSG0000001003018
ELF4 / Q99607 / E74 like ETS transcription factor 4ENSG0000010203418
SPDEF / O95238 / SAM pointed domain containing ETS transcription factorENSG0000012466417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR003118  Pointed domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR033071  ETS homologous factor
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050673 epithelial cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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