ENSG00000135374


Homo sapiens

Features
Gene ID: ENSG00000135374
  
Biological name :ELF5
  
Synonyms : E74 like ETS transcription factor 5 / ELF5 / Q9UKW6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p13
Gene start: 34478793
Gene end: 34513805
  
Corresponding Affymetrix probe sets: 220624_s_at (Human Genome U133 Plus 2.0 Array)   220625_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484521
Ensembl peptide - ENSP00000311010
Ensembl peptide - ENSP00000407589
Ensembl peptide - ENSP00000436386
Ensembl peptide - ENSP00000257832
NCBI entrez gene - 2001     See in Manteia.
OMIM - 605169
RefSeq - XM_017017309
RefSeq - NM_001243080
RefSeq - NM_001243081
RefSeq - NM_001422
RefSeq - NM_198381
RefSeq - XM_017017308
RefSeq Peptide - NP_001413
RefSeq Peptide - NP_001230010
RefSeq Peptide - NP_001230009
RefSeq Peptide - NP_938195
swissprot - A0A087X1W9
swissprot - A8K443
swissprot - Q9UKW6
Ensembl - ENSG00000135374
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ELF5ENSGALG00000035867Gallus gallus
 Elf5ENSMUSG00000027186Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EHF / Q9NZC4 / ETS homologous factorENSG0000013537343
ELF3 / P78545 / E74 like ETS transcription factor 3ENSG0000016343532
ETV6 / P41212 / ETS variant 6ENSG0000013908323
ELF2 / Q15723 / E74 like ETS transcription factor 2ENSG0000010938120
ETV7 / Q9Y603 / ETS variant 7ENSG0000001003020
SPDEF / O95238 / SAM pointed domain containing ETS transcription factorENSG0000012466420
ELF4 / Q99607 / E74 like ETS transcription factor 4ENSG0000010203418
ELF1 / P32519 / E74 like ETS transcription factor 1ENSG0000012069017


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR003118  Pointed domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR033069  ETS-related transcription factor Elf-5
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001712 ectodermal cell fate commitment IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0007398 ectoderm development IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0045596 negative regulation of cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060644 mammary gland epithelial cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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