ENSG00000120690


Homo sapiens

Features
Gene ID: ENSG00000120690
  
Biological name :ELF1
  
Synonyms : E74 like ETS transcription factor 1 / ELF1 / P32519
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q14.11
Gene start: 40932028
Gene end: 41061440
  
Corresponding Affymetrix probe sets: 212418_at (Human Genome U133 Plus 2.0 Array)   212420_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000489586
Ensembl peptide - ENSP00000239882
Ensembl peptide - ENSP00000384135
Ensembl peptide - ENSP00000486912
Ensembl peptide - ENSP00000487240
NCBI entrez gene - 1997     See in Manteia.
OMIM - 189973
RefSeq - XM_017020413
RefSeq - XM_005266277
RefSeq - XM_011534950
RefSeq - XM_011534951
RefSeq - XM_017020409
RefSeq - XM_017020410
RefSeq - XM_017020411
RefSeq - XM_017020412
RefSeq - NM_001145353
RefSeq - NM_172373
RefSeq - XM_005266276
RefSeq Peptide - NP_758961
RefSeq Peptide - NP_001138825
swissprot - Q5T9E7
swissprot - A0A0U1RRL5
swissprot - P32519
swissprot - A0A024RDU6
swissprot - A0A0D9SG85
Ensembl - ENSG00000120690
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ELF1ENSGALG00000016947Gallus gallus
 Elf1ENSMUSG00000036461Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELF4 / Q99607 / E74 like ETS transcription factor 4ENSG0000010203439
ELF2 / Q15723 / E74 like ETS transcription factor 2ENSG0000010938136
ELF3 / P78545 / E74 like ETS transcription factor 3ENSG0000016343511
ETV7 / Q9Y603 / ETS variant 7ENSG0000001003010
SPDEF / O95238 / SAM pointed domain containing ETS transcription factorENSG0000012466410
ETV6 / P41212 / ETS variant 6ENSG0000013908310
EHF / Q9NZC4 / ETS homologous factorENSG000001353739
ELF5 / Q9UKW6 / E74 like ETS transcription factor 5ENSG000001353747


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR022084  Transcription factor Elf, N-terminal
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001817 regulation of cytokine production IEA
 biological_processGO:0001959 regulation of cytokine-mediated signaling pathway TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated NAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050855 regulation of B cell receptor signaling pathway TAS
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates transcription of genes involved in BCR signaling
RUNX1 regulates transcription of genes involved in interleukin signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000067955 CBFB / Q13951 / core-binding factor beta subunit  / reaction / complex
 ENSG00000159216 RUNX1 / Q01196 / runt related transcription factor 1  / reaction / complex






 

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