ENSMUSG00000036461


Mus musculus

Features
Gene ID: ENSMUSG00000036461
  
Biological name :Elf1
  
Synonyms : Elf1 / ETS-related transcription factor Elf-1 / Q60775
  
Possible biological names infered from orthology : E74 like ETS transcription factor 1 / P32519
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: D3
Gene start: 79481194
Gene end: 79582494
  
Corresponding Affymetrix probe sets: 10416657 (MoGene1.0st)   1417540_at (Mouse Genome 430 2.0 Array)   1439319_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000046515
Ensembl peptide - ENSMUSP00000106459
Ensembl peptide - ENSMUSP00000153956
NCBI entrez gene - 13709     See in Manteia.
MGI - MGI:107180
RefSeq - XM_011244948
RefSeq - NM_001286411
RefSeq - NM_001286412
RefSeq - NM_007920
RefSeq - XM_011244946
RefSeq - XM_011244947
RefSeq Peptide - NP_001273340
RefSeq Peptide - NP_001273341
RefSeq Peptide - NP_031946
swissprot - Q3V1H4
swissprot - Q60775
Ensembl - ENSMUSG00000036461
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ELF1ENSGALG00000016947Gallus gallus
 ELF1ENSG00000120690Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Elf4 / Q9Z2U4 / ETS-related transcription factor Elf-4 / Q99607* / E74 like ETS transcription factor 4*ENSMUSG0000003110337
Elf2 / Q9JHC9 / ETS-related transcription factor Elf-2 / Q15723* / E74 like ETS transcription factor 2*ENSMUSG0000003717435
Elf3 / Q3UPW2 / ETS-related transcription factor Elf-3 / P78545* / E74 like ETS transcription factor 3*ENSMUSG0000000305111
Spdef / Q9WTP3 / SAM pointed domain-containing Ets transcription factor / O95238*ENSMUSG0000002421511
Ehf / O70273 / ETS homologous factor / Q9NZC4*ENSMUSG0000001235010
Etv6 / P97360 / Transcription factor ETV6 / P41212* / ETS variant 6*ENSMUSG0000003019910
Elf5 / Q8VDK3 / ETS-related transcription factor Elf-5 / Q9UKW6* / E74 like ETS transcription factor 5*ENSMUSG000000271868


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR022084  Transcription factor Elf, N-terminal
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001817 regulation of cytokine production IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway IGI
 cellular_componentGO:0005634 nucleus ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates transcription of genes involved in interleukin signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002144 abnormal B lymphocyte development "atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tal1Hpt/Tal1Hpt
Genetic Background: (C57BL/6J x C3FeLe.B6-a/a)F1

 MP:0002459 abnormal B cell physiology "abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tal1Hpt/Tal1Hpt
Genetic Background: (C57BL/6J x C3FeLe.B6-a/a)F1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031885 Cbfb / Q08024 / Core-binding factor subunit beta / Q13951* / core-binding factor beta subunit*  / complex / reaction






 

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