Manteia

ENSMUSG00000030199

Mus musculus

Features

Gene ID:	ENSMUSG00000030199

Biological name :	Etv6

Synonyms :	Etv6 / P97360 / Transcription factor ETV6

Possible biological names infered from orthology :	ETS variant 6 / P41212

Species:	Mus musculus

Chr. number:	6
Strand:	1
Band:	G1
Gene start:	134035700
Gene end:	134270158

Corresponding Affymetrix probe sets:	10542275 (MoGene1.0st) 1423401_at (Mouse Genome 430 2.0 Array) 1434880_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000130761 Ensembl peptide - ENSMUSP00000079818 Ensembl peptide - ENSMUSP00000107594 NCBI entrez gene - 14011 See in Manteia. MGI - MGI:109336 RefSeq - XM_011241208 RefSeq - NM_001303102 RefSeq - NM_007961 RefSeq - XM_011241206 RefSeq - XM_011241207 RefSeq Peptide - NP_031987 RefSeq Peptide - NP_001290031 swissprot - E9QAJ7 swissprot - P97360 swissprot - E9Q8J8 Ensembl - ENSMUSG00000030199

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
ETV6	ENSGALG00000012921	Gallus gallus
ETV6	ENSG00000139083	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Spdef / Q9WTP3 / SAM pointed domain-containing Ets transcription factor / O95238*	ENSMUSG00000024215	15
Elf3 / Q3UPW2 / ETS-related transcription factor Elf-3 / P78545* / E74 like ETS transcription factor 3*	ENSMUSG00000003051	14
Elf4 / Q9Z2U4 / ETS-related transcription factor Elf-4 / Q99607* / E74 like ETS transcription factor 4*	ENSMUSG00000031103	14
Elf2 / Q9JHC9 / ETS-related transcription factor Elf-2 / Q15723* / E74 like ETS transcription factor 2*	ENSMUSG00000037174	14
Elf1 / Q60775 / ETS-related transcription factor Elf-1 / P32519* / E74 like ETS transcription factor 1*	ENSMUSG00000036461	13
Ehf / O70273 / ETS homologous factor / Q9NZC4*	ENSMUSG00000012350	13
Elf5 / Q8VDK3 / ETS-related transcription factor Elf-5 / Q9UKW6* / E74 like ETS transcription factor 5*	ENSMUSG00000027186	12

Protein motifs (from Interpro)

Interpro ID	Name
IPR000418	Ets domain
IPR003118	Pointed domain
IPR013761	Sterile alpha motif/pointed domain superfamily
IPR036388	Winged helix-like DNA-binding domain superfamily
IPR036390	Winged helix DNA-binding domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II	IEA
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IEA
biological_process	GO:0006366	transcription by RNA polymerase II	IEA
biological_process	GO:0007296	vitellogenesis	IMP
biological_process	GO:0022008	neurogenesis	IMP
biological_process	GO:0030154	cell differentiation	IDA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA
biological_process	GO:0071425	hematopoietic stem cell proliferation	IEA
biological_process	GO:0097152	mesenchymal cell apoptotic process	IMP
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005730	nucleolus	IEA
cellular_component	GO:0005829	cytosol	IEA
molecular_function	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	IEA
molecular_function	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	IDA
molecular_function	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding	IDA
molecular_function	GO:0003677	DNA binding	IEA
molecular_function	GO:0003700	DNA-binding transcription factor activity	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0019904	protein domain specific binding	IEA
molecular_function	GO:0043565	sequence-specific DNA binding	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000222	decreased neutrophil count	"fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Etv6^tm2.1Sho/Etv6^tm2.1Sho Genetic Background: involves: 129S1/Sv Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0000229	abnormal megakaryocyte differentiation	"atypical process of formation and development these very large bone marrow cells which release mature platelets" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Etv6^tm2.1Sho/Etv6^tm2.1Sho Genetic Background: involves: 129S1/Sv
MP:0000245	abnormal erythropoiesis	"atypical process of red blood cell formation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]	Show Allelic Composition: Etv6^tm2.1Sho/Etv6^tm2.1Sho Genetic Background: involves: 129S1/Sv
MP:0000291	enlarged pericardium	"extended fibroserous membrane covering the heart and beginning of the great vessels" [J:29971]	Show Allelic Composition: Eng^tm1Hma/Eng^tm1Hma Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0001577	anemia	"less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Runx1^tm3Spe/Runx1^tm3Spe,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * CBA
MP:0001718	abnormal yolk sac	"malformed extraembryonic tissue which contributes to hematopoietic circulation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:12623]	Show Allelic Composition: Eng^tm1Hma/Eng^tm1Hma Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0001719	absent vitelline blood vessels	"missing vasculature of the yolk sac" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:62571, J:12623]	Show Allelic Composition: Eng^tm1Hma/Eng^tm1Hma Genetic Background: involves: 129P2/OlaHsd * C57BL/6J Allelic Composition: Etv6^tm2.1Sho/Etv6^tm2.1Sho Genetic Background: involves: 129S1/Sv
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6^{tm1(RUNX1)Haho} Genetic Background: B6.129S1-Etv6^{tm1(Runx1)Haho}
MP:0001802	arrested B cell development	"inability to produce mature B cells, and accumulation of B cell precursors" [J:52607]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0001884	mammary alveolar hyperplasia		Show Allelic Composition: Nfe2l2^tm1Mym/Nfe2l2^tm1Mym,n-TUtca2^tm2Mym/n-TUtca2^tm2.1Mym,Lyz2^tm1(cre)Ifo/Lyz2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
MP:0002026	leukemia	"progressive proliferation of abnormal leukocytes in hematopoietic tissues, organs and blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18542]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Gata1-cre)1Sho/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CD-1 * Swiss Webster Allelic Composition: Etv6^{tm1.1(RUNX1,hsb5)Lvdw}/Etv6⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J Allelic Composition: Etv6^{tm1.1(RUNX1,hsb5)Lvdw}/Etv6⁺,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
MP:0002082	postnatal lethality	"premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6^{tm1(RUNX1)Haho} Genetic Background: B6.129S1-Etv6^{tm1(Runx1)Haho}
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Etv6^{tm3(NTRK3)Sho}/Etv6⁺,Tg(Wap-cre)11738Mam/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Runx1^tm3Spe/Runx1^tm3Spe,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * CBA Allelic Composition: Etv6^{tm1.1(RUNX1,hsb5)Lvdw}/Etv6⁺,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
MP:0002123	abnormal hematopoiesis	"abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Gata1-cre)1Sho/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CD-1 * Swiss Webster
MP:0002144	abnormal B lymphocyte development	"atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6^{tm1(RUNX1)Haho} Genetic Background: B6.129S1-Etv6^{tm1(Runx1)Haho}
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Etv6^tm2.1Sho/Etv6^tm2.1Sho Genetic Background: involves: 129S1/Sv
MP:0002401	abnormal lymphopoiesis	"atypcial formation of lymphocytes and plasma cells from lymphoid stem cells which develop from the pluripotent hematopoietic stem cells in the bone marrow; these lymphoid stem cells differentiate into T-lymphocytes; B-lymphocytes; plasma cells; or NK-cells (natural killer cells), depending on the organ or tissues to which they migrate" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Gata1-cre)1Sho/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CD-1 * Swiss Webster
MP:0002414	abnormal myeloblast morphology/development	"anomalous structure, formation, or numbers of the cells found in the bone marrow that give rise to the granulocyte line of blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0003179	decreased platelet count	"fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]	Show Allelic Composition: Etv6^tm2.1Sho/Etv6^tm2.1Sho Genetic Background: involves: 129S1/Sv Allelic Composition: Etv6^tm2Sho/Etv6^tm2Sho,Tg(Mx1-cre)1Cgn/? Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0003288	intestinal edema	"an accumulation of an excessive amount of serous fluid in the intestine or intestinal cells " [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6^{tm1(RUNX1)Haho} Genetic Background: B6.129S1-Etv6^{tm1(Runx1)Haho}
MP:0003984	embryonic growth retardation	"slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Eng^tm1Hma/Eng^tm1Hma Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0004499	increased incidence of chemically-induced tumors	"higher than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0004809	increased hematopoietic stem cell number	"greater cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Vav1-cre)1Graf/0 Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Runx1^tm3Spe/Runx1⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * CBA
MP:0004810	decreased hematopoietic stem cell number	"reduced cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Runx1^tm3Spe/Runx1^tm3Spe,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * CBA
MP:0005016	decreased lymphocyte number	"fewer than normal white blood cell numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0005017	decreased B cell number	"fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Vav1-cre)1Graf/0 Genetic Background: involves: 129S1/Sv * C57BL/6
MP:0005481	chronic myelocytic leukemia	"a heterogeneous group of myeloproliferative disorders that may evolve into acute leukemia in late stages " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Etv6^{tm3(NTRK3)Sho}/Etv6⁺,Tg(Wap-cre)11738Mam/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL
MP:0006410	abnormal common myeloid progenitor cell morphology	"anomaly in the structure of the hematopoietic stem cells that are capable of forming any of the myeloid lineage cells (erythrocytes, granulocytes, thrombocytes, monocytes, and mast cells) but not cells of the lymphoid lineage" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0008208	decreased pro-B cell number	"reduced number of the progenitor cells of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but are not yet fully committed to the B cell lineage until the expression of PAX5 occurs" [CL:0000826, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Vav1-cre)1Graf/0 Genetic Background: involves: 129S1/Sv * C57BL/6
MP:0008209	decreased pre-B cell number	"reduced number of the cells in the B lymphocyte lineage that have undergone VDJ rearrangement of the immunoglobulin heavy chain and are in the process of V-J rearrangement of the light chain: these cells express mu heavy chain on the cell surface" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Vav1-cre)1Graf/0 Genetic Background: involves: 129S1/Sv * C57BL/6
MP:0008249	abnormal common lymphocyte progenitor cell morphology	"any structural anomaly of a progenitor cell committed to the lymphoid lineage" [CL:0000051, PMID:10407577]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0008973	decreased erythroid progenitor cell number	"reduced numbers of progenitors of the erythrocyte lineage" [CL:0000038, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0009278	abnormal bone marrow cell physiology	"any functional anomaly of any of the cells found in the blood" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0010299	increased mammary gland tumor incidence	"greater than the expected number of neoplasms in the mammary gland, usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Nfe2l2^tm1Mym/Nfe2l2^tm1Mym,n-TUtca2^tm2Mym/n-TUtca2^tm2.1Mym,Lyz2^tm1(cre)Ifo/Lyz2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 Allelic Composition: Etv6^{tm3(NTRK3)Sho}/Etv6⁺,Tg(Wap-cre)11738Mam/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL
MP:0010373	myeloid hyperplasia	"greater than normal number of nucleated cells of the myeloid lineage (a monocyte, granulocyte, or mast cell), found in blood or other tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0011091	complete prenatal lethality	"death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Etv6^tm2.1Sho/Etv6^tm2.1Sho Genetic Background: involves: 129S1/Sv Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6^{tm1(RUNX1)Haho} Genetic Background: B6.129S1-Etv6^{tm1(Runx1)Haho}
MP:0011098	complete embryonic lethality during organogenesis	"death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Eng^tm1Hma/Eng^tm1Hma Genetic Background: involves: 129P2/OlaHsd * C57BL/6J Allelic Composition: Etv6^{tm1.1(RUNX1,hsb5)Lvdw}/Etv6^{tm1.1(RUNX1,hsb5)Lvdw} Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J
MP:0011108	partial embryonic lethality during organogenesis	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Etv6^tm2.1Sho/Etv6^tm2.1Sho Genetic Background: involves: 129S1/Sv Allelic Composition: Etv6^{tm1(RUNX1)Haho}/Etv6⁺,Tg(Gata1-cre)1Sho/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CD-1 * Swiss Webster
MP:0011110	partial preweaning lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Etv6^{tm1.1(RUNX1,hsb5)Lvdw}/Etv6^{tm1.1(RUNX1,hsb5)Lvdw} Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr