ENSMUSG00000037174


Mus musculus

Features
Gene ID: ENSMUSG00000037174
  
Biological name :Elf2
  
Synonyms : Elf2 / ETS-related transcription factor Elf-2 / Q9JHC9
  
Possible biological names infered from orthology : E74 like ETS transcription factor 2 / Q15723
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: C
Gene start: 51252720
Gene end: 51340663
  
Corresponding Affymetrix probe sets: 10498038 (MoGene1.0st)   1418275_a_at (Mouse Genome 430 2.0 Array)   1418276_at (Mouse Genome 430 2.0 Array)   1428045_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141197
Ensembl peptide - ENSMUSP00000139360
Ensembl peptide - ENSMUSP00000141525
Ensembl peptide - ENSMUSP00000142300
Ensembl peptide - ENSMUSP00000061076
Ensembl peptide - ENSMUSP00000088678
Ensembl peptide - ENSMUSP00000103686
Ensembl peptide - ENSMUSP00000103688
Ensembl peptide - ENSMUSP00000126871
Ensembl peptide - ENSMUSP00000139199
Ensembl peptide - ENSMUSP00000139358
NCBI entrez gene - 69257     See in Manteia.
MGI - MGI:1916507
RefSeq - XM_017319714
RefSeq - NM_001291059
RefSeq - NM_001291062
RefSeq - NM_001291063
RefSeq - NM_023502
RefSeq - XM_006502031
RefSeq - XM_006502034
RefSeq - XM_006502035
RefSeq - XM_011240222
RefSeq - XM_017319713
RefSeq Peptide - NP_075991
RefSeq Peptide - NP_001277988
RefSeq Peptide - NP_001277991
RefSeq Peptide - NP_001277992
swissprot - A0A0A6YY68
swissprot - Q9JHC9
swissprot - V9GXK9
swissprot - V9GXW8
swissprot - A0A0A6YWF3
swissprot - Q3TVH6
swissprot - Q80UM8
swissprot - A0A0B4J1G5
Ensembl - ENSMUSG00000037174
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elf2aENSDARG00000019459Danio rerio
 elf2bENSDARG00000079626Danio rerio
 ELF2ENSGALG00000009774Gallus gallus
 ELF2ENSG00000109381Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Elf1 / Q60775 / ETS-related transcription factor Elf-1 / P32519* / E74 like ETS transcription factor 1*ENSMUSG0000003646137
Elf4 / Q9Z2U4 / ETS-related transcription factor Elf-4 / Q99607* / E74 like ETS transcription factor 4*ENSMUSG0000003110332
Elf3 / Q3UPW2 / ETS-related transcription factor Elf-3 / P78545* / E74 like ETS transcription factor 3*ENSMUSG0000000305112
Ehf / O70273 / ETS homologous factor / Q9NZC4*ENSMUSG0000001235011
Spdef / Q9WTP3 / SAM pointed domain-containing Ets transcription factor / O95238*ENSMUSG0000002421511
Etv6 / P97360 / Transcription factor ETV6 / P41212* / ETS variant 6*ENSMUSG0000003019911
Elf5 / Q8VDK3 / ETS-related transcription factor Elf-5 / Q9UKW6* / E74 like ETS transcription factor 5*ENSMUSG000000271869


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR022084  Transcription factor Elf, N-terminal
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II ISS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016604 nuclear body ISO
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding ISO


Pathways (from Reactome)
Pathway description
RUNX1 regulates transcription of genes involved in BCR signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031885 Cbfb / Q08024 / Core-binding factor subunit beta / Q13951* / core-binding factor beta subunit*  / complex / reaction






 

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contact: otassy@igbmc.fr