ENSG00000109381


Homo sapiens

Features
Gene ID: ENSG00000109381
  
Biological name :ELF2
  
Synonyms : E74 like ETS transcription factor 2 / ELF2 / Q15723
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q31.1
Gene start: 139028112
Gene end: 139177218
  
Corresponding Affymetrix probe sets: 203822_s_at (Human Genome U133 Plus 2.0 Array)   210361_s_at (Human Genome U133 Plus 2.0 Array)   242735_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000377782
Ensembl peptide - ENSP00000397796
Ensembl peptide - ENSP00000426997
Ensembl peptide - ENSP00000426087
Ensembl peptide - ENSP00000421278
Ensembl peptide - ENSP00000351458
Ensembl peptide - ENSP00000368867
Ensembl peptide - ENSP00000368868
NCBI entrez gene - 1998     See in Manteia.
RefSeq - XM_017007861
RefSeq - XM_005262805
RefSeq - XM_006714128
RefSeq - XM_006714129
RefSeq - XM_011531710
RefSeq - XM_011531711
RefSeq - XM_011531712
RefSeq - XM_017007856
RefSeq - XM_017007857
RefSeq - XM_017007858
RefSeq - XM_017007859
RefSeq - XM_017007860
RefSeq - NM_001276457
RefSeq - NM_001276458
RefSeq - NM_001276459
RefSeq - NM_006874
RefSeq - NM_201999
RefSeq - XM_005262803
RefSeq - XM_005262804
RefSeq Peptide - NP_001263388
RefSeq Peptide - NP_001317965
RefSeq Peptide - NP_006865
RefSeq Peptide - NP_973728
RefSeq Peptide - NP_001263386
RefSeq Peptide - NP_001263387
swissprot - D6RGD9
swissprot - D6R9B1
swissprot - Q15723
swissprot - B7Z720
swissprot - D6RHI1
Ensembl - ENSG00000109381
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elf2aENSDARG00000019459Danio rerio
 elf2bENSDARG00000079626Danio rerio
 ELF2ENSGALG00000009774Gallus gallus
 Elf2ENSMUSG00000037174Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELF1 / P32519 / E74 like ETS transcription factor 1ENSG0000012069037
ELF4 / Q99607 / E74 like ETS transcription factor 4ENSG0000010203432
ELF3 / P78545 / E74 like ETS transcription factor 3ENSG0000016343512
SPDEF / O95238 / SAM pointed domain containing ETS transcription factorENSG0000012466411
EHF / Q9NZC4 / ETS homologous factorENSG0000013537311
ETV6 / P41212 / ETS variant 6ENSG0000013908311
ETV7 / Q9Y603 / ETS variant 7ENSG0000001003010
ELF5 / Q9UKW6 / E74 like ETS transcription factor 5ENSG000001353749


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR022084  Transcription factor Elf, N-terminal
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0050855 regulation of B cell receptor signaling pathway TAS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016604 nuclear body IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates transcription of genes involved in BCR signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000067955 CBFB / Q13951 / core-binding factor beta subunit  / complex / reaction
 ENSG00000159216 RUNX1 / Q01196 / runt related transcription factor 1  / complex / reaction






 

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