ENSG00000135457


Homo sapiens

Features
Gene ID: ENSG00000135457
  
Biological name :TFCP2
  
Synonyms : Q12800 / TFCP2 / transcription factor CP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.13
Gene start: 51093663
Gene end: 51173134
  
Corresponding Affymetrix probe sets: 207627_s_at (Human Genome U133 Plus 2.0 Array)   209338_at (Human Genome U133 Plus 2.0 Array)   227637_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449742
Ensembl peptide - ENSP00000257915
Ensembl peptide - ENSP00000447991
Ensembl peptide - ENSP00000449280
NCBI entrez gene - 7024     See in Manteia.
OMIM - 189889
RefSeq - NM_005653
RefSeq - NM_001173452
RefSeq - NM_001173453
RefSeq Peptide - NP_001166923
RefSeq Peptide - NP_005644
RefSeq Peptide - NP_001166924
swissprot - Q12800
swissprot - A0A024R120
swissprot - F8VWL0
swissprot - F8VX55
Ensembl - ENSG00000135457
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tfcp2ENSDARG00000060306Danio rerio
 Tfcp2ENSMUSG00000009733Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBP1 / Q9NZI7 / upstream binding protein 1ENSG0000015356074
Q9NZI6 / TFCP2L1 / transcription factor CP2 like 1ENSG0000011511270
GRHL2 / Q6ISB3 / grainyhead like transcription factor 2ENSG0000008330725
GRHL1 / Q9NZI5 / grainyhead like transcription factor 1ENSG0000013431724
GRHL3 / Q8TE85 / grainyhead like transcription factor 3ENSG0000015805521


Protein motifs (from Interpro)
Interpro ID Name
 IPR007604  CP2 transcription factor
 IPR013761  Sterile alpha motif/pointed domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0042789 mRNA transcription by RNA polymerase II IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0032991 protein-containing complex IMP
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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