ENSG00000135773


Homo sapiens

Features
Gene ID: ENSG00000135773
  
Biological name :CAPN9
  
Synonyms : calpain 9 / CAPN9 / O14815
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q42.2
Gene start: 230747384
Gene end: 230802003
  
Corresponding Affymetrix probe sets: 208063_s_at (Human Genome U133 Plus 2.0 Array)   210641_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355626
Ensembl peptide - ENSP00000271971
Ensembl peptide - ENSP00000346538
NCBI entrez gene - 10753     See in Manteia.
OMIM - 606401
RefSeq - XM_017000099
RefSeq - NM_001319676
RefSeq - NM_006615
RefSeq - NM_016452
RefSeq - XM_011544017
RefSeq - XM_011544018
RefSeq - XM_011544019
RefSeq - XM_011544020
RefSeq - XM_017000098
RefSeq Peptide - NP_001306605
RefSeq Peptide - NP_006606
RefSeq Peptide - NP_057536
swissprot - O14815
swissprot - E7ESS6
Ensembl - ENSG00000135773
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capn9ENSDARG00000012341Danio rerio
 Capn9ENSMUSG00000031981Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAPN3 / P20807 / calpain 3ENSG0000009252956
CAPN1 / P07384 / calpain 1ENSG0000001421654
CAPN2 / P17655 / calpain 2ENSG0000016290951
CAPN8 / A6NHC0 / calpain 8ENSG0000020369750
CAPN11 / Q9UMQ6 / calpain 11ENSG0000013722548
CAPN12 / Q6ZSI9 / calpain 12ENSG0000018247239
A8MX76 / CAPN14 / calpain 14ENSG0000021471138
CAPN5 / O15484 / calpain 5ENSG0000014926031
CAPN13 / Q6MZZ7 / calpain 13ENSG0000016294930
CAPN6 / Q9Y6Q1 / calpain 6ENSG0000007727427


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022683  Peptidase C2, calpain, domain III
 IPR022684  Peptidase C2, calpain family
 IPR029542  Calpain-9
 IPR033883  Calpain subdomain III
 IPR036213  Calpain large subunit, domain III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007586 digestion IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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